{"id":"W3049025034","doi":"10.1371/journal.pgen.1008752","title":"Transcriptional regulators of the Golli/myelin basic protein locus integrate additive and stealth activities","year":2020,"lang":"en","type":"article","venue":"PLoS Genetics","topic":"RNA Research and Splicing","field":"Biochemistry, Genetics and Molecular Biology","cited_by":8,"is_retracted":false,"has_abstract":true,"ca_institutions":"Toronto General Hospital; Lunenfeld-Tanenbaum Research Institute; University of Toronto; Mount Sinai Hospital; McGill University","funders":"Canadian Institutes of Health Research; McGill University","keywords":"Biology; Locus (genetics); Myelin basic protein; Computational biology; Genetics; Cell biology; Myelin; Neuroscience; Gene; Central nervous system","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0000652563,0.0001046672,0.000116409,0.00001551612,0.00006254968,0.00001375673,0.0001514056,0.00007227727,0.00001910723],"category_scores_gemma":[0.00006348184,0.00007697017,0.00005671571,0.00007831085,0.0001691679,0.000002588557,0.0000737935,0.0001204304,0.000001145844],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000008103015,"about_ca_system_score_gemma":0.0001362632,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00000641233,"about_ca_topic_score_gemma":0.00003326207,"domain_scores_codex":[0.9992015,0.00008762451,0.0001433083,0.0002049663,0.0001917616,0.0001708703],"domain_scores_gemma":[0.9996085,0.00001005757,0.00005755447,0.0001582034,0.00006358829,0.0001021477],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009016541,0.00002481366,0.0006536215,0.00005230948,0.00004650222,7.4613e-7,0.0001583376,0.00001776924,0.9962865,0.0001147097,0.000202756,0.002351758],"study_design_scores_gemma":[0.0002997227,0.0003113271,0.001421961,0.00003364365,0.00001284379,0.000001588832,0.0003329917,0.00100331,0.9944723,0.00005750002,0.001963304,0.00008952719],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9976639,0.0008650554,0.0001674368,0.000712311,0.00001874096,0.0003083851,0.0001204358,0.000004716415,0.0001390206],"genre_scores_gemma":[0.9988079,0.0002065781,0.0002231171,0.0001880229,0.0001252465,0.0000201564,0.00001847127,0.00001556435,0.0003949208],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002262231,"threshold_uncertainty_score":0.3138753,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01783570904350341,"score_gpt":0.2313924534207343,"score_spread":0.2135567443772309,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}