{"id":"W3049025034","doi":"10.1371/journal.pgen.1008752","title":"Transcriptional regulators of the Golli/myelin basic protein locus integrate additive and stealth activities","year":2020,"lang":"en","type":"article","venue":"PLoS Genetics","topic":"RNA Research and Splicing","field":"Biochemistry, Genetics and Molecular Biology","cited_by":8,"is_retracted":false,"has_abstract":true,"ca_institutions":"Toronto General Hospital; Lunenfeld-Tanenbaum Research Institute; University of Toronto; Mount Sinai Hospital; McGill University","funders":"Canadian Institutes of Health Research; McGill University","keywords":"Biology; Locus (genetics); Myelin basic protein; Computational biology; Genetics; Cell biology; Myelin; Neuroscience; Gene; Central nervous system","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002466102,0.0006443936,0.0002458889,0.0006235431,0.0001430496,0.0002665368,0.0004395085,0.0003109426,0.00164316],"category_scores_gemma":[0.000199429,0.0003473562,0.0004118145,0.0002373649,0.0005286439,0.0002308388,0.0006468066,0.0006533929,0.0008728952],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004361063,"about_ca_system_score_gemma":0.0002746845,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003527426,"about_ca_topic_score_gemma":0.0007083235,"domain_scores_codex":[0.999564,0.00004418936,0.00002765463,0.0001160043,0.0001304813,0.0001176404],"domain_scores_gemma":[0.9996459,0.00007866839,0.0001197358,0.00005551771,0.00002582513,0.00007425747],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005550637,0.00001871698,0.0001819085,0.00001082786,0.000001879697,0.00002950078,0.00001234269,0.00006500043,0.99853,0.0002728297,0.00001164861,0.000809784],"study_design_scores_gemma":[0.00003585528,0.0002053521,0.004152633,0.000008391108,0.00002154463,0.0002596422,0.00002939633,0.002915007,0.9889657,0.0001479711,0.003246947,0.00001155577],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9802302,0.0008347551,0.01557692,0.0000599102,0.00002842991,0.00006912542,0.0004464255,0.0004375872,0.002316706],"genre_scores_gemma":[0.9857246,0.0003021646,0.007877707,0.00006659131,0.0000148951,0.00006796249,0.001037599,0.0001366121,0.004771892],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00164316,"threshold_uncertainty_score":0.00549686,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01783570904350341,"score_gpt":0.2313924534207343,"score_spread":0.2135567443772309,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}