{"id":"W3049052172","doi":"10.1126/science.abc3421","title":"Microbiome-derived inosine modulates response to checkpoint inhibitor immunotherapy","year":2020,"lang":"en","type":"article","venue":"Science","topic":"Cancer Immunotherapy and Biomarkers","field":"Medicine","cited_by":1341,"is_retracted":false,"has_abstract":true,"ca_institutions":"Centre Hospitalier de l’Université de Montréal; Alberta Children's Hospital; University of Calgary","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; Alberta Innovates; Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung","keywords":"Inosine; Immunotherapy; Microbiome; Computational biology; Chemistry; Biology; Immunology; Immune system; Bioinformatics; Biochemistry; Adenosine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01902200474979086,"score_gpt":0.2797730999589675,"score_spread":0.2607510952091767,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}