{"id":"W3049166125","doi":"10.1101/2020.08.14.247296","title":"Single-cell dynamics of pannexin-1-facilitated programmed ATP loss during apoptosis","year":2020,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Phagocytosis and Immune Regulation","field":"Immunology and Microbiology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University","funders":"Japan Society for the Promotion of Science; Ministry of Education, Culture, Sports, Science and Technology; Japan Agency for Medical Research and Development","keywords":"Pannexin; Intracellular; Cell biology; Apoptosis; Adenosine triphosphate; Cytosol; Glycolysis; Caspase; Programmed cell death; Biology; Chemistry; Biochemistry; Metabolism; Gap junction; Enzyme","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001636945,0.0001237009,0.0003162189,0.000129369,0.0001069591,0.0002539871,0.0002323713,0.0002702498,0.0007154008],"category_scores_gemma":[0.0001951969,0.00009288445,0.0001206127,0.0001173767,0.0001982863,0.0003158242,0.0001769922,0.0004510154,0.0002400535],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003988867,"about_ca_system_score_gemma":0.00008701149,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003024698,"about_ca_topic_score_gemma":0.000254451,"domain_scores_codex":[0.9998964,0.00001152439,0.000004662113,0.00003421622,0.00003164377,0.00002164102],"domain_scores_gemma":[0.9999108,0.00002660328,0.00002050014,0.00001148098,0.00001628096,0.00001427984],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001054913,0.00001235092,0.0004332098,0.00002026895,0.000003111224,0.00008966873,0.00003961589,0.0002200643,0.9968721,0.0001146684,0.00005056147,0.0020389],"study_design_scores_gemma":[0.00001509462,0.0001050423,0.007925531,0.000004909404,0.000005365549,0.0002412385,0.00006048783,0.008661731,0.9818652,0.0002046818,0.000902858,0.00000776864],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9914932,0.0007006652,0.006969674,0.00008188064,0.00001973525,0.000009962753,0.0001447073,0.0000650922,0.0005149652],"genre_scores_gemma":[0.9959996,0.0002545009,0.002603844,0.00002789642,0.000006727656,0.00001669961,0.00009916821,0.00001208668,0.0009793799],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007154008,"threshold_uncertainty_score":0.002894163,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01621949995593604,"score_gpt":0.206657416690938,"score_spread":0.1904379167350019,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}