{"id":"W3049255020","doi":"10.1007/s00253-020-10589-w","title":"Transcriptomic and proteomic profiling response of methicillin-resistant Staphylococcus aureus (MRSA) to a novel bacteriocin, plantaricin GZ1-27 and its inhibition of biofilm formation","year":2020,"lang":"en","type":"article","venue":"Applied Microbiology and Biotechnology","topic":"Bacterial biofilms and quorum sensing","field":"Biochemistry, Genetics and Molecular Biology","cited_by":42,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Calgary","funders":"","keywords":"Biofilm; Microbiology; Staphylococcus aureus; Bacteriocin; Biology; Methicillin-resistant Staphylococcus aureus; Bacteria; Transcriptome; Biochemistry; Gene; Gene expression; Antimicrobial; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009465007,0.0001841298,0.0003237484,0.0001840346,0.0001351774,0.0002267392,0.00007971078,0.0001966567,0.0006257948],"category_scores_gemma":[0.0001482078,0.00008943569,0.0002817231,0.0003144613,0.000116733,0.0001657379,0.0001205042,0.000285762,0.0001546318],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001133788,"about_ca_system_score_gemma":0.0001969781,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009516621,"about_ca_topic_score_gemma":0.001041086,"domain_scores_codex":[0.9999036,0.000008360733,0.000007761761,0.00002324214,0.00003313512,0.00002393222],"domain_scores_gemma":[0.9999338,0.00001491455,0.00001627069,0.000002582915,0.0000177899,0.00001472948],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001168971,0.00001014678,0.0002561233,0.00002348027,0.000002429962,0.00002777758,0.00001062099,0.00003123087,0.9991252,0.0000100934,0.00001631801,0.0003697478],"study_design_scores_gemma":[0.00002196916,0.0009682625,0.1243856,0.0000199419,0.00007986753,0.000534003,0.0004328777,0.002745593,0.8681769,0.0001294735,0.00247929,0.00002625361],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9950749,0.0008642721,0.001094387,0.0001063653,0.00002968987,0.00002183964,0.002172506,0.00001821611,0.0006179491],"genre_scores_gemma":[0.9895551,0.001087174,0.00220413,0.0001660849,0.00002315633,0.00006897765,0.003711603,0.00001009713,0.003173703],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009516621,"threshold_uncertainty_score":0.002093494,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01188191295055642,"score_gpt":0.2105303435634629,"score_spread":0.1986484306129065,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}