{"id":"W3049302966","doi":"10.1158/1557-3265.bladder19-ia10","title":"Abstract IA10: Developing rational combination therapy with checkpoint inhibitors","year":2020,"lang":"en","type":"article","venue":"Clinical Cancer Research","topic":"Cancer Immunotherapy and Biomarkers","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Ottawa Regional Cancer Foundation; Ottawa Hospital","funders":"","keywords":"Dasatinib; Cabozantinib; Medicine; Immunotherapy; Cancer research; In vivo; Druggability; Combination therapy; Cancer; Cancer immunotherapy; Melanoma; Pharmacology; Internal medicine; Imatinib; Biology; Myeloid leukemia","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002438273,0.0007092627,0.0004767737,0.0004923027,0.0001184195,0.0005407649,0.000510084,0.0003090353,0.002671303],"category_scores_gemma":[0.0001515464,0.0002300674,0.0003365465,0.0002992897,0.0001418972,0.0002633362,0.0003001321,0.0008570097,0.0009916943],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005377139,"about_ca_system_score_gemma":0.0005542511,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000672582,"about_ca_topic_score_gemma":0.001446057,"domain_scores_codex":[0.9998902,0.00001679265,0.000007500491,0.00002745,0.0000311512,0.0000269356],"domain_scores_gemma":[0.9999496,0.00000517032,0.00001107493,0.00000474201,0.00001030067,0.00001911706],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.002341245,0.002196611,0.001905982,0.000809042,0.0002653986,0.0003992624,0.00006118559,0.02450545,0.6938674,0.003618225,0.009329853,0.2607004],"study_design_scores_gemma":[0.003193005,0.01812859,0.005069871,0.0001683943,0.0005936141,0.001614372,0.00005568912,0.08966691,0.7510319,0.001793149,0.1285812,0.0001033651],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"other","genre_scores_codex":[0.8696404,0.02902657,0.05404199,0.001760259,0.0007066087,0.001538226,0.002177599,0.001560168,0.0395482],"genre_scores_gemma":[0.9560682,0.00930518,0.02288184,0.0004688542,0.000103309,0.000483584,0.00133806,0.00009470016,0.009256345],"genre_candidate":"other","genre_consensus":null,"teacher_disagreement_score":0.002671303,"threshold_uncertainty_score":0.008936405,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.3418735799590187,"score_gpt":0.5133392790341231,"score_spread":0.1714656990751044,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}