{"id":"W3049410166","doi":"10.1038/s41589-020-0612-z","title":"Targeted self-destruction","year":2020,"lang":"en","type":"letter","venue":"Nature Chemical Biology","topic":"Glycosylation and Glycoproteins Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Alberta","funders":"","keywords":"Glycan; Neuraminidase; Glycosylation; Immune system; Immunity; Antibody; Biology; In vivo; Chemistry; Cell biology; Glycoprotein; Immunology; Biochemistry; Genetics; Virus","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":["research_integrity"],"category_scores_codex":[0.00006285238,0.0003529875,0.0003330957,0.00007635877,0.00005687623,0.00002396128,0.0005081543,0.005480692,0.0001992449],"category_scores_gemma":[0.0003972928,0.0003152914,0.0002124443,0.0001804084,0.0001497031,0.000001856718,0.000248553,0.004076035,0.0001455734],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004401321,"about_ca_system_score_gemma":0.0001475909,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000004505488,"about_ca_topic_score_gemma":7.505334e-7,"domain_scores_codex":[0.998034,0.0001353787,0.0002644579,0.0008770934,0.0002014623,0.0004876045],"domain_scores_gemma":[0.9991071,0.00002830548,0.0001191226,0.0004488593,0.0001793477,0.000117269],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00003757205,0.000008971117,0.00002974312,0.00003731602,0.00006561971,0.00002493519,0.000002406201,5.030428e-8,0.4354686,0.00001921691,0.5637715,0.0005340817],"study_design_scores_gemma":[0.0002578857,0.0001104878,0.000005902905,0.000004759889,0.00001433095,0.00003463725,0.000001009941,0.000007273598,0.2787911,0.0003317819,0.7201928,0.000248025],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.0197577,0.003939662,0.0001666513,0.9682038,0.001429153,0.0008759179,0.0003668185,0.0002686401,0.004991583],"genre_scores_gemma":[0.08670674,0.0003116186,0.002765674,0.8722399,0.01548663,0.00009032296,0.02117047,0.0001117445,0.001116915],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.1566775,"threshold_uncertainty_score":0.9999299,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007163965570151465,"score_gpt":0.2674447420242331,"score_spread":0.2602807764540816,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}