{"id":"W3049535451","doi":"10.1096/fj.202001145r","title":"Maresin 1 resolves aged‐associated macrophage inflammation to improve bone regeneration","year":2020,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Bone Metabolism and Diseases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":52,"is_retracted":false,"has_abstract":true,"ca_institutions":"Toronto Rehabilitation Institute; University of Toronto","funders":"National Institute on Aging; Duke University","keywords":"Macrophage; Inflammation; Regeneration (biology); Chemistry; Cell biology; Immunology; Medicine; Biology; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002631928,0.0001010306,0.00009714108,0.00002097512,0.0002148371,0.0001004022,0.000149479,0.00006277002,0.00004283416],"category_scores_gemma":[0.0003846513,0.00007322717,0.00008101574,0.00009394656,0.00002626722,0.000008074813,0.00007048611,0.0001190216,0.00002401219],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001027136,"about_ca_system_score_gemma":0.00006461139,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000006857775,"about_ca_topic_score_gemma":0.00001328889,"domain_scores_codex":[0.99917,0.0001544269,0.0002048804,0.00014404,0.0001594479,0.0001671799],"domain_scores_gemma":[0.9994574,0.000007763964,0.000117942,0.0001511223,0.00007934227,0.0001864276],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001872056,0.00001300017,0.0001910951,0.000003562784,0.00002525336,0.00001317634,0.0001317001,0.0001972946,0.9858662,0.00002205647,0.00984579,0.00350368],"study_design_scores_gemma":[0.0005985984,0.0001586176,0.005911063,0.000007637689,0.00004292499,0.00001866568,0.00009814936,0.0001432597,0.9876771,0.00008688053,0.005134373,0.000122751],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9925249,0.001293017,0.002148561,0.00349975,0.00016544,0.0001281149,0.00005186553,0.00001158637,0.0001768204],"genre_scores_gemma":[0.9959878,0.000140874,0.0002566078,0.001698363,0.001368864,0.000006172315,0.000091522,0.00001465442,0.0004351301],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005719968,"threshold_uncertainty_score":0.2986117,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009981385625947274,"score_gpt":0.22485826828374,"score_spread":0.2148768826577928,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}