{"id":"W3049608341","doi":"10.1210/clinem/dgaa526","title":"Maintenance of Acromegaly Control in Patients Switching From Injectable Somatostatin Receptor Ligands to Oral Octreotide","year":2020,"lang":"en","type":"article","venue":"The Journal of Clinical Endocrinology & Metabolism","topic":"Pituitary Gland Disorders and Treatments","field":"Medicine","cited_by":103,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"","keywords":"Acromegaly; Placebo; Medicine; Octreotide; Somatostatin; Internal medicine; Gastroenterology; Clinical endpoint; Growth hormone; Endocrinology; Hormone; Clinical trial; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001289082,0.0004562391,0.001686086,0.0001746099,0.0002088727,0.0004659702,0.0002696737,0.0004283105,0.001794075],"category_scores_gemma":[0.001077555,0.0001822896,0.0006502427,0.0002168064,0.0004325492,0.0003335471,0.0001523469,0.0009701434,0.0002395078],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003697339,"about_ca_system_score_gemma":0.0005436743,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005723665,"about_ca_topic_score_gemma":0.001353668,"domain_scores_codex":[0.9996096,0.0001662157,0.00003337172,0.0000577415,0.00005811152,0.00007494108],"domain_scores_gemma":[0.9993433,0.0002091305,0.0001901219,0.00004097739,0.00003202743,0.0001843974],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"observational","study_design_scores_codex":[0.7338759,0.008372405,0.0307883,0.001085981,0.001480219,0.0002913352,0.0002018758,0.001392501,0.05684549,0.0001258237,0.001594533,0.1639457],"study_design_scores_gemma":[0.302154,0.5871684,0.09849957,0.0001168038,0.0009830307,0.0008784326,0.0001147762,0.001563426,0.005943191,0.0001522657,0.002384979,0.00004108488],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9969494,0.002226933,0.00008977545,0.00008397956,0.00003152888,0.0001216636,0.00008827394,0.00001862043,0.000389958],"genre_scores_gemma":[0.9984988,0.0005353163,0.0002057289,0.0002005558,0.00005694012,0.0001004554,0.000181449,0.000003372778,0.0002173695],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001794075,"threshold_uncertainty_score":0.0068174,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02824192219329572,"score_gpt":0.3271529411683135,"score_spread":0.2989110189750178,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}