{"id":"W3049725010","doi":"10.1007/s13204-020-01526-4","title":"Molecular level investigation of curcumin self-assembly induced by trigonelline and nanoparticle formation","year":2020,"lang":"en","type":"article","venue":"Applied Nanoscience","topic":"Curcumin's Biomedical Applications","field":"Biochemistry, Genetics and Molecular Biology","cited_by":20,"is_retracted":false,"has_abstract":false,"ca_institutions":"Memorial University of Newfoundland","funders":"","keywords":"Trigonelline; Curcumin; Nanoparticle; Drug delivery; Nanotechnology; Biocompatible material; Chemistry; Materials science; Pharmacology; Medicine; Organic chemistry; Biochemistry; Biomedical engineering","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008410079,0.0001797853,0.0001352448,0.0001400369,0.0001270681,0.0001283147,0.0002220155,0.000273385,0.001428374],"category_scores_gemma":[0.0001493937,0.00009756057,0.0001793883,0.00011787,0.000186199,0.0001609643,0.0001068981,0.000324413,0.0002589466],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000352385,"about_ca_system_score_gemma":0.0001216447,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001066685,"about_ca_topic_score_gemma":0.001147331,"domain_scores_codex":[0.9999288,0.000007513023,0.00000339748,0.00002049701,0.00001948362,0.00002021336],"domain_scores_gemma":[0.9999256,0.00001736823,0.00002805501,0.000007260075,0.0000126454,0.000009155748],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006779577,0.000009427473,0.00008890246,0.00003538198,0.000003662384,0.00003958178,0.00002022565,0.00008205049,0.9991104,0.0001022941,0.00002792509,0.0004123219],"study_design_scores_gemma":[0.00000539763,0.0001017423,0.001198806,0.000002336738,0.000008340145,0.00003060539,0.00001475524,0.001216547,0.9969115,0.00002164674,0.0004840338,0.000004341785],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9958566,0.0004198774,0.001552921,0.00005288408,0.00001472788,0.0000155582,0.0001121469,0.00006808543,0.001907129],"genre_scores_gemma":[0.9976742,0.0001595191,0.0009504627,0.00001950353,0.000002808437,0.00001400029,0.00006214284,0.00000909479,0.001108305],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001428374,"threshold_uncertainty_score":0.004778385,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0217788238848437,"score_gpt":0.2376087292197883,"score_spread":0.2158299053349446,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}