{"id":"W3049768172","doi":"10.14740/jh721","title":"Ofatumumab and Complement Replacement in Relapsed/Refractory Chronic Lymphocytic Leukemia","year":2020,"lang":"en","type":"article","venue":"Journal of Hematology","topic":"Complement system in diseases","field":"Immunology and Microbiology","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Ofatumumab; Medicine; Tolerability; Chronic lymphocytic leukemia; Internal medicine; Adverse effect; Oncology; Complement system; Immunology; Surrogate endpoint; Gastroenterology; Antibody; Leukemia","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008133879,0.0002824248,0.0006587605,0.0001897581,0.0001961684,0.0002485278,0.0002541879,0.0002644695,0.0009913896],"category_scores_gemma":[0.0004523937,0.00006997339,0.0002662445,0.0002137444,0.000180169,0.0001444367,0.0001839113,0.000514949,0.0001283807],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004310836,"about_ca_system_score_gemma":0.0003945186,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000603009,"about_ca_topic_score_gemma":0.002110617,"domain_scores_codex":[0.9997408,0.0001475067,0.00001884036,0.00002207884,0.00003089105,0.00003993918],"domain_scores_gemma":[0.9997029,0.0001109534,0.00007720596,0.00001570091,0.00002221586,0.00007105875],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"observational","study_design_scores_codex":[0.1387795,0.01009592,0.05148744,0.001667358,0.001185586,0.001053503,0.0003027251,0.002314065,0.08722132,0.0004162897,0.003828884,0.7016473],"study_design_scores_gemma":[0.1021445,0.5578499,0.2333837,0.0004897335,0.002011311,0.009518698,0.0002706322,0.005601769,0.04648241,0.0007482746,0.04142508,0.00007409166],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9869791,0.01147377,0.000159033,0.0002483272,0.00003492968,0.00009649177,0.00006264723,0.0000129826,0.0009326464],"genre_scores_gemma":[0.9963859,0.002477575,0.0003622638,0.0001939844,0.00006520743,0.0000599882,0.0001060918,0.000002330651,0.000346588],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009913896,"threshold_uncertainty_score":0.004301667,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02170536600382994,"score_gpt":0.2660745219923109,"score_spread":0.244369155988481,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}