{"id":"W3056154005","doi":"10.1080/15476286.2020.1809196","title":"Regulation of human telomerase RNA biogenesis and localization","year":2020,"lang":"en","type":"review","venue":"RNA Biology","topic":"Telomeres, Telomerase, and Senescence","field":"Medicine","cited_by":26,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Jewish General Hospital","funders":"Canadian Institutes of Health Research","keywords":"Telomere; Biology; Telomerase; Ribonucleoprotein; RNA; Telomerase RNA component; Biogenesis; Telomerase reverse transcriptase; Cell biology; Transcription (linguistics); Computational biology; Genetics; Reverse transcriptase; Non-coding RNA; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001478842,0.0003417815,0.001823675,0.0003338985,0.00007406742,0.000006951044,0.000116672,0.0005234088,0.0001337188],"category_scores_gemma":[0.0001376612,0.0002677692,0.0002269987,0.000500561,0.0002451213,0.00003018634,0.00006880779,0.0001795194,0.00002771337],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005993037,"about_ca_system_score_gemma":0.0001702293,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00009151163,"about_ca_topic_score_gemma":0.000009108508,"domain_scores_codex":[0.9982047,0.0001933218,0.0007569892,0.0005063915,0.0001146921,0.0002238696],"domain_scores_gemma":[0.99882,0.000101259,0.0004710686,0.0003449932,0.0001020254,0.0001606458],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00001999938,0.0000454402,0.0004159417,0.008275748,0.0001558628,0.00001468902,0.00005066337,8.957569e-8,0.004264648,0.0006982305,0.000327247,0.9857314],"study_design_scores_gemma":[0.0004128409,0.0004145374,0.0004998,0.003079927,0.0009488482,0.00009001247,0.00001350975,0.00002213357,0.0007604848,0.0001043065,0.9933589,0.0002947086],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0008317312,0.9976538,0.0002296418,0.00008136503,0.0001553437,0.0006100546,0.00008480867,0.00006226589,0.0002910218],"genre_scores_gemma":[0.007298707,0.990783,0.0001947065,0.0001137249,0.0003033762,0.00002129265,0.001087417,0.00004609012,0.000151634],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9930316,"threshold_uncertainty_score":0.9999775,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05397814093010272,"score_gpt":0.3475614868875006,"score_spread":0.2935833459573979,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}