{"id":"W3056154005","doi":"10.1080/15476286.2020.1809196","title":"Regulation of human telomerase RNA biogenesis and localization","year":2020,"lang":"en","type":"review","venue":"RNA Biology","topic":"Telomeres, Telomerase, and Senescence","field":"Medicine","cited_by":26,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Jewish General Hospital","funders":"Canadian Institutes of Health Research","keywords":"Telomere; Biology; Telomerase; Ribonucleoprotein; RNA; Telomerase RNA component; Biogenesis; Telomerase reverse transcriptase; Cell biology; Transcription (linguistics); Computational biology; Genetics; Reverse transcriptase; Non-coding RNA; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002836266,0.0004632165,0.0005417846,0.00104679,0.0001404154,0.0005292784,0.0004320817,0.0005218248,0.002078883],"category_scores_gemma":[0.0002932914,0.0001447365,0.0002183014,0.0009175241,0.0002284535,0.0005654586,0.0004282088,0.0007317174,0.00176405],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003733953,"about_ca_system_score_gemma":0.0006063629,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004817595,"about_ca_topic_score_gemma":0.0007270607,"domain_scores_codex":[0.9999033,0.00001313044,0.00001402816,0.00001918103,0.00003937595,0.00001097429],"domain_scores_gemma":[0.9998971,0.00003699379,0.00002427318,0.000003609992,0.00002519968,0.00001279895],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00004731213,0.00002636644,0.0001524671,0.01160809,0.00004792898,0.0001649295,0.00004302115,0.0002466054,0.008326542,0.004075743,0.02082396,0.9544371],"study_design_scores_gemma":[0.000009573401,0.00006411155,0.001018674,0.001531574,0.00006538265,0.001090089,0.00002217966,0.00006815287,0.001835723,0.001237528,0.9930438,0.00001320452],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001435769,0.9984933,0.0001381195,0.0001299177,0.0001095091,0.000003160758,0.00002153513,0.000008461571,0.0009523209],"genre_scores_gemma":[0.001060673,0.9978283,0.0001675219,0.0001255205,0.0001154208,0.000005753061,0.00004859845,0.000001441524,0.000646778],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002078883,"threshold_uncertainty_score":0.00695461,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05397814093010272,"score_gpt":0.3475614868875006,"score_spread":0.2935833459573979,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}