{"id":"W3076015961","doi":"10.1101/2020.08.20.259960","title":"FACT is recruited to the +1 nucleosome of transcribed genes and spreads in a Chd1-dependent manner","year":2020,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Genomics and Chromatin Dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":11,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; Montreal Clinical Research Institute","funders":"Biotechnology and Biological Sciences Research Council; Canadian Institutes of Health Research; Fonds de Recherche du Québec - Santé; Compute Canada","keywords":"Nucleosome; Chromatin; RNA polymerase II; Histone; Cell biology; Saccharomyces cerevisiae; Transcription (linguistics); Biology; Genetics; Gene; Chaperone (clinical); Computational biology; Promoter; Gene expression","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0000809437,0.0001799419,0.0001725097,0.0001580961,0.0001811386,0.0003145828,0.00021022,0.0001686542,0.001838361],"category_scores_gemma":[0.0001578439,0.0002659086,0.0001975416,0.0001317193,0.0002118571,0.0002030973,0.000232705,0.0002232056,0.0004025451],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003482938,"about_ca_system_score_gemma":0.0001929547,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002719361,"about_ca_topic_score_gemma":0.00390066,"domain_scores_codex":[0.9999362,0.000003641766,0.000002037561,0.00002678839,0.00002010706,0.00001117517],"domain_scores_gemma":[0.9999342,0.00001100633,0.00001662524,0.00001186293,0.00001307412,0.00001325248],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006034417,0.000006489262,0.00295593,0.00004159476,0.000009127009,0.00009720827,0.00003031455,0.001263488,0.993006,0.0004943946,0.0001342136,0.001900765],"study_design_scores_gemma":[0.00001686566,0.00006157503,0.03540142,0.00001226115,0.00001719584,0.0004065743,0.00008304424,0.02049069,0.9386584,0.0004532378,0.004385209,0.00001357384],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9840782,0.000496451,0.01243388,0.00007283369,0.0000139159,0.000008721886,0.0003080458,0.0001560801,0.002431836],"genre_scores_gemma":[0.9933745,0.0002396706,0.004079622,0.00002659912,0.000003954882,0.000006562151,0.000534234,0.00002606809,0.001708837],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002719361,"threshold_uncertainty_score":0.006149888,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01396249471889464,"score_gpt":0.2177104324425727,"score_spread":0.2037479377236781,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}