{"id":"W3077714497","doi":"10.1093/nar/gkaa675","title":"Activation of viral transcription by stepwise largescale folding of an RNA virus genome","year":2020,"lang":"en","type":"article","venue":"Nucleic Acids Research","topic":"Viral Infections and Immunology Research","field":"Medicine","cited_by":9,"is_retracted":false,"has_abstract":true,"ca_institutions":"York University","funders":"Natural Sciences and Engineering Research Council of Canada; York University","keywords":"Biology; Subgenomic mRNA; RNA; Transcription (linguistics); RNA-dependent RNA polymerase; Non-coding RNA; Genetics; RNA editing; Genome; RNA-induced transcriptional silencing; Capsid; RNA silencing; Base pair; Computational biology; Gene; RNA interference","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002358525,0.0002001842,0.0001985172,0.0000933298,0.0001778038,0.0004170328,0.0001474489,0.000174099,0.0006833754],"category_scores_gemma":[0.0003060645,0.0001789391,0.0002483203,0.00007491634,0.0002919067,0.0002545709,0.000363592,0.0004567837,0.000351034],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002698468,"about_ca_system_score_gemma":0.0002295881,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001734899,"about_ca_topic_score_gemma":0.0004473252,"domain_scores_codex":[0.9998549,0.00003493457,0.000007136319,0.00003420951,0.000041938,0.00002683568],"domain_scores_gemma":[0.9998437,0.00006461184,0.00002498882,0.00003129611,0.00001468045,0.0000206913],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003889762,0.00001612717,0.000363173,0.00002416558,0.000002920815,0.00005947146,0.00002831752,0.0007473102,0.9951432,0.0009616215,0.00002642921,0.002588306],"study_design_scores_gemma":[0.0000151872,0.0002298721,0.002310842,0.000009362358,0.000007961909,0.0001690918,0.00004773762,0.01116388,0.9827566,0.0008824338,0.00239447,0.00001247785],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9580811,0.001115453,0.03718742,0.0001132921,0.00005063472,0.00005289754,0.000061135,0.0002933747,0.003044798],"genre_scores_gemma":[0.9878523,0.0002730048,0.0109479,0.00002942547,0.00001317152,0.00002318165,0.00005725974,0.00002853878,0.0007752347],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0006833754,"threshold_uncertainty_score":0.002286077,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0770979518408922,"score_gpt":0.3662440753880121,"score_spread":0.2891461235471199,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}