{"id":"W3080363070","doi":"10.1016/j.jogc.2019.11.069","title":"Committee Opinion No. 406: Prenatal Testing After IVF With Preimplantation Genetic Testing for Aneuploidy","year":2020,"lang":"en","type":"article","venue":"Journal of Obstetrics and Gynaecology Canada","topic":"Prenatal Screening and Diagnostics","field":"Medicine","cited_by":22,"is_retracted":false,"has_abstract":false,"ca_institutions":"Sinai Health System","funders":"Canadian Institutes of Health Research; Genome Canada","keywords":"Aneuploidy; Genetic testing; In vitro fertilisation; Preimplantation genetic diagnosis; Advanced maternal age; Obstetrics; Medicine; Genetic counseling; Biology; Population; Gynecology; Genetics; Pregnancy; Fetus; Chromosome","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaresearch"],"consensus_categories":[],"category_scores_codex":[0.00008814706,0.0001172678,0.000272959,0.00007091132,0.00007908977,0.00002036716,0.00006970161,0.00007083058,0.00001074057],"category_scores_gemma":[0.01705521,0.00009128042,0.00002079246,0.000250305,0.00003317111,0.00006225863,0.00003034032,0.000247078,3.939068e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001486823,"about_ca_system_score_gemma":0.0008738672,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002214175,"about_ca_topic_score_gemma":0.001151312,"domain_scores_codex":[0.9990786,0.00002321181,0.0003367108,0.000133175,0.0002215602,0.0002067311],"domain_scores_gemma":[0.9938884,0.004873824,0.0002966084,0.00006322474,0.0005929771,0.0002850127],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0001254143,0.00004471386,0.9057709,0.0004166458,0.00009553918,0.002213509,0.00009178865,0.000491761,0.00006960146,0.000004361052,0.001580179,0.08909561],"study_design_scores_gemma":[0.00330672,0.005026456,0.9833236,0.00008396125,0.000176667,0.0006234606,0.00007343236,0.004723001,0.000106492,0.00001727815,0.002389772,0.0001492098],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9929239,0.002541371,0.00115318,0.0005087019,0.001959636,0.0003314218,0.00007052812,0.00001315945,0.0004980622],"genre_scores_gemma":[0.9698848,0.00001414612,0.02906485,0.0008492027,0.000144027,0.00000643605,0.00001122944,0.00001527558,0.00001011225],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.08894639,"threshold_uncertainty_score":0.9912245,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02574379739012042,"score_gpt":0.2367480954884719,"score_spread":0.2110042980983515,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}