{"id":"W3080507748","doi":"10.1097/j.pain.0000000000002052","title":"Metabolomic analysis coupled with extreme phenotype sampling identified that lysophosphatidylcholines are associated with multisite musculoskeletal pain","year":2020,"lang":"en","type":"article","venue":"Pain","topic":"Fibromyalgia and Chronic Fatigue Syndrome Research","field":"Medicine","cited_by":23,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba; Memorial University of Newfoundland","funders":"Canadian Institutes of Health Research; Memorial University of Newfoundland; Research and Development Corporation of Newfoundland and Labrador","keywords":"Metabolomics; Phenotype; Medicine; Musculoskeletal pain; Bioinformatics; Biology; Physical therapy; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005897813,0.0004649672,0.0003144116,0.0007296671,0.0003053361,0.000599984,0.0002433384,0.0004149414,0.001050798],"category_scores_gemma":[0.001137514,0.0001689508,0.0003606621,0.0005687163,0.0002323698,0.0001837443,0.000562001,0.0003678095,0.0001392026],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001889804,"about_ca_system_score_gemma":0.0001868659,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003110373,"about_ca_topic_score_gemma":0.004748343,"domain_scores_codex":[0.999671,0.0001057522,0.00002988132,0.00008306695,0.0000689814,0.00004126207],"domain_scores_gemma":[0.9994387,0.0001001708,0.0002545102,0.00005872892,0.00008447653,0.00006337146],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0008905136,0.00008176342,0.9533459,0.00006781245,0.0003480797,0.0004415899,0.0000953513,0.0001739334,0.03561375,0.00004577563,0.0001553891,0.008740195],"study_design_scores_gemma":[0.00001066121,0.00013063,0.9975268,0.0000060026,0.00006608514,0.0004948026,0.000045079,0.0004345694,0.001144393,0.000031706,0.0001053258,0.00000391597],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9979926,0.0002395247,0.00121964,0.00004831106,0.000003447547,0.00001398713,0.0003023426,0.000008358089,0.0001718025],"genre_scores_gemma":[0.9986872,0.00007117025,0.0008826601,0.00003071941,0.00000458354,0.000008507941,0.0001885577,0.000002600464,0.0001239393],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003110373,"threshold_uncertainty_score":0.006184578,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05895656086312676,"score_gpt":0.2918745989483773,"score_spread":0.2329180380852506,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}