{"id":"W3080539263","doi":"10.1139/bcb-2020-0090","title":"hCINAP is potentially a direct target gene of HIF-1 and is required for hypoxia-induced EMT and apoptosis in cervical cancer cells","year":2020,"lang":"en","type":"article","venue":"Biochemistry and Cell Biology","topic":"Cancer, Hypoxia, and Metabolism","field":"Biochemistry, Genetics and Molecular Biology","cited_by":15,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Hypoxia (environmental); Cancer research; Epithelial–mesenchymal transition; Metastasis; Aryl hydrocarbon receptor nuclear translocator; Biology; Cervical cancer; PI3K/AKT/mTOR pathway; Apoptosis; Cancer cell; Protein kinase B; Hypoxia-inducible factors; Cell biology; Signal transduction; Cancer; Chemistry; Gene; Transcription factor; Aryl hydrocarbon receptor; Genetics","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006710434,0.0001469984,0.000168107,0.0001707754,0.0002453327,0.0001691551,0.0001204402,0.0001776692,0.001979857],"category_scores_gemma":[0.0001100692,0.00009318787,0.000171277,0.0001357344,0.0001602856,0.0001679555,0.0001592505,0.0002938417,0.000263737],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003416066,"about_ca_system_score_gemma":0.0002373583,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008126058,"about_ca_topic_score_gemma":0.001341224,"domain_scores_codex":[0.9999307,0.00000621091,0.000003584319,0.00001871674,0.00002541155,0.00001534605],"domain_scores_gemma":[0.9999254,0.00001177321,0.00002179245,0.000005599341,0.0000127876,0.00002262107],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005671429,0.00001038158,0.0007994725,0.00005409352,0.000003870805,0.0001640776,0.00001660337,0.00003444922,0.9970239,0.0001650153,0.00009271001,0.001578722],"study_design_scores_gemma":[0.00002129282,0.0002534827,0.05987487,0.00001606681,0.00002709218,0.001790658,0.00009519039,0.001248348,0.9205148,0.0002076571,0.01594046,0.0000100671],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9819924,0.004828573,0.006821466,0.0001766617,0.00005313784,0.00005253759,0.001262928,0.0001330341,0.004679304],"genre_scores_gemma":[0.9919094,0.001004395,0.002082773,0.00008381616,0.00001574222,0.00004740931,0.00177189,0.00001528468,0.003069328],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001979857,"threshold_uncertainty_score":0.006623268,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01300350154067356,"score_gpt":0.2412946770205296,"score_spread":0.228291175479856,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}