{"id":"W3080551885","doi":"10.1093/jac/dkaa360","title":"Multiplex real-time PCR assays for the prediction of cephalosporin, ciprofloxacin and azithromycin antimicrobial susceptibility of positive <i>Neisseria gonorrhoeae</i> nucleic acid amplification test samples","year":2020,"lang":"en","type":"article","venue":"Journal of Antimicrobial Chemotherapy","topic":"Reproductive tract infections research","field":"Immunology and Microbiology","cited_by":29,"is_retracted":false,"has_abstract":true,"ca_institutions":"Inuit Tapiriit Kanatami; Queen Elizabeth II Health Sciences Centre; Public Health Agency of Canada; Toronto Public Health; BC Centre for Disease Control; Public Health Ontario; Ste. Anne's Hospital; Provincial Laboratory of Public Health","funders":"Public Health Agency of Canada","keywords":"Neisseria gonorrhoeae; Nucleic Acid Amplification Tests; MTRR; Cephalosporin; Ciprofloxacin; Microbiology; Azithromycin; Biology; Neisseria; Multiplex; Agar dilution; Multiplex polymerase chain reaction; Virology; Antimicrobial; Chlamydia trachomatis; Polymerase chain reaction; Genotype; Antibiotics; Genetics; Bacteria; Minimum inhibitory concentration; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002731989,0.001344224,0.0007686921,0.001423271,0.0002171762,0.0008293304,0.0008252328,0.0007722596,0.001498773],"category_scores_gemma":[0.00441586,0.0006507895,0.0007550875,0.0006244131,0.0006848955,0.0003498791,0.0004384709,0.0008814771,0.0007743801],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0009264118,"about_ca_system_score_gemma":0.0005045328,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001115898,"about_ca_topic_score_gemma":0.002587936,"domain_scores_codex":[0.9946572,0.001223656,0.0004820761,0.001729116,0.001555502,0.0003523241],"domain_scores_gemma":[0.9963027,0.001373007,0.0009801115,0.0003572852,0.0008411929,0.0001456143],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001538588,0.0006822218,0.09827325,0.000291994,0.0002522139,0.0002123933,0.0003013052,0.003664676,0.8581664,0.0003125698,0.000997671,0.03530683],"study_design_scores_gemma":[0.0001211784,0.00213187,0.0882912,0.00009998595,0.0003487999,0.001025785,0.000118251,0.04540769,0.8565771,0.0002908011,0.005489259,0.00009806234],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8632727,0.001613125,0.1238704,0.0002189787,0.0001790526,0.00104336,0.004949114,0.001534799,0.003318455],"genre_scores_gemma":[0.7681475,0.0005978662,0.2187786,0.0004664031,0.0001021346,0.001414715,0.007362167,0.0001224176,0.00300822],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002731989,"threshold_uncertainty_score":0.01444834,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02617037082403361,"score_gpt":0.2696672193760989,"score_spread":0.2434968485520653,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}