{"id":"W3080551885","doi":"10.1093/jac/dkaa360","title":"Multiplex real-time PCR assays for the prediction of cephalosporin, ciprofloxacin and azithromycin antimicrobial susceptibility of positive <i>Neisseria gonorrhoeae</i> nucleic acid amplification test samples","year":2020,"lang":"en","type":"article","venue":"Journal of Antimicrobial Chemotherapy","topic":"Reproductive tract infections research","field":"Immunology and Microbiology","cited_by":29,"is_retracted":false,"has_abstract":true,"ca_institutions":"Inuit Tapiriit Kanatami; Queen Elizabeth II Health Sciences Centre; Public Health Agency of Canada; Toronto Public Health; BC Centre for Disease Control; Public Health Ontario; Ste. Anne's Hospital; Provincial Laboratory of Public Health","funders":"Public Health Agency of Canada","keywords":"Neisseria gonorrhoeae; Nucleic Acid Amplification Tests; MTRR; Cephalosporin; Ciprofloxacin; Microbiology; Azithromycin; Biology; Neisseria; Multiplex; Agar dilution; Multiplex polymerase chain reaction; Virology; Antimicrobial; Chlamydia trachomatis; Polymerase chain reaction; Genotype; Antibiotics; Genetics; Bacteria; Minimum inhibitory concentration; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009695797,0.0002644736,0.0006975955,0.0001662405,0.0002221282,0.00002982829,0.0003535914,0.0002513507,0.0001497153],"category_scores_gemma":[0.0006224393,0.0002044992,0.0002999556,0.0003829397,0.0006965989,0.0002886028,0.0000528215,0.0004385456,0.000009238318],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007623312,"about_ca_system_score_gemma":0.0002018901,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001428538,"about_ca_topic_score_gemma":0.000009880254,"domain_scores_codex":[0.9979445,0.0002335178,0.001047729,0.0004012901,0.00006290669,0.0003100662],"domain_scores_gemma":[0.9966876,0.0007450362,0.001082649,0.0003594266,0.001073852,0.00005147367],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002650352,0.0006288229,0.01792165,0.0001333687,0.0004588538,3.412142e-7,0.00121164,0.00003401388,0.9701136,0.00002070119,0.004694955,0.002131639],"study_design_scores_gemma":[0.002930754,0.00123374,0.09913216,0.00008039797,0.0001123731,0.00009793723,0.000173544,0.00003416113,0.8947186,0.00001949821,0.001331239,0.0001355834],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9921339,0.0002363628,0.002470018,0.003071689,0.0002775833,0.001030588,0.0007143599,0.00002596393,0.00003951175],"genre_scores_gemma":[0.9964259,0.001434393,0.001611326,0.000136002,0.0002207914,0.000005620744,0.00008057534,0.000042935,0.00004250298],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0812105,"threshold_uncertainty_score":0.8339233,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02617037082403361,"score_gpt":0.2696672193760989,"score_spread":0.2434968485520653,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}