{"id":"W3080677031","doi":"10.1128/msphere.00748-20","title":"Antibiotic Resistance in Vibrio cholerae: Mechanistic Insights from IncC Plasmid-Mediated Dissemination of a Novel Family of Genomic Islands Inserted at <i>trmE</i>","year":2020,"lang":"en","type":"article","venue":"mSphere","topic":"Vibrio bacteria research studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":37,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Sherbrooke","funders":"Fonds de Recherche du Québec - Santé; Canadian Institutes of Health Research; Natural Sciences and Engineering Research Council of Canada; Government of Canada","keywords":"Vibrio cholerae; Plasmid; Cholera; Biology; Antibiotic resistance; Mobile genetic elements; Genomic island; Multiple drug resistance; Microbiology; Drug resistance; Genetics; Gene; Virology; Antibiotics; Bacteria","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001604635,0.0002827804,0.0001656852,0.0002009291,0.0002019801,0.0004680598,0.0002850642,0.000511083,0.0007639924],"category_scores_gemma":[0.0001186649,0.0001233001,0.0002307944,0.00009554976,0.0005399282,0.0003824557,0.000212636,0.0004659116,0.0001834663],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004451738,"about_ca_system_score_gemma":0.0002830672,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008591056,"about_ca_topic_score_gemma":0.0008024322,"domain_scores_codex":[0.9999434,0.000007979265,0.000001791664,0.00001141925,0.00001511411,0.00002025315],"domain_scores_gemma":[0.9999375,0.00001441822,0.00001500822,0.000008331949,0.000008878435,0.00001581625],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001619548,0.00008732123,0.001444279,0.0001864614,0.0000128136,0.000642176,0.0001431243,0.000510243,0.9887756,0.003294347,0.0001238857,0.004617844],"study_design_scores_gemma":[0.00009437025,0.001456737,0.05689302,0.0001059441,0.00008193878,0.004296392,0.001307968,0.01414922,0.8986112,0.006063789,0.01688745,0.00005185637],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9773112,0.009301382,0.007572563,0.001235721,0.00004775896,0.00003560757,0.0001943545,0.00009132574,0.004210147],"genre_scores_gemma":[0.9958049,0.001938128,0.0011321,0.0001075877,0.00001055909,0.00001176378,0.0001089928,0.000004883404,0.0008811086],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008591056,"threshold_uncertainty_score":0.003229976,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01177353161314927,"score_gpt":0.2392122820354617,"score_spread":0.2274387504223124,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}