{"id":"W3080718656","doi":"10.1242/jcs.249201","title":"Mammalian copper homeostasis requires retromer-dependent recycling of the high-affinity copper transporter 1","year":2020,"lang":"en","type":"article","venue":"Journal of Cell Science","topic":"Trace Elements in Health","field":"Nursing","cited_by":59,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Medical Research Council; Lister Institute of Preventive Medicine; Medical Research Council Canada; Wellcome Trust","keywords":"Biology; Retromer; Transporter; Endosome; Homeostasis; Copper; ATP7A; Cell biology; Biochemistry; Intracellular; Gene","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001994865,0.0001487303,0.0003422764,0.0001276591,0.0003041683,0.0000608703,0.001150094,0.00006581756,0.000158087],"category_scores_gemma":[0.0002947282,0.0001004434,0.0001578078,0.0008393589,0.0004808445,0.000566974,0.00006713216,0.0005656824,0.000009398036],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002196537,"about_ca_system_score_gemma":0.0003217525,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005054885,"about_ca_topic_score_gemma":0.00002619692,"domain_scores_codex":[0.9965668,0.0001508445,0.0009582471,0.0002647287,0.001613199,0.0004462138],"domain_scores_gemma":[0.9979619,0.0001246757,0.0009858328,0.0003244434,0.0002915477,0.0003115832],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0008375442,0.0003603326,0.07138914,0.0003094741,0.0000260518,0.00004855552,0.008667718,0.001028221,0.8969195,0.0001194801,0.006487795,0.01380622],"study_design_scores_gemma":[0.001320826,0.001118112,0.1683852,0.0002439896,0.0001001773,0.00004112945,0.001220698,0.00006437306,0.822557,0.0002118435,0.004496902,0.0002398263],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9803235,0.0002283307,0.00006460573,0.01619686,0.002236875,0.0001732975,0.00001546613,0.00001172692,0.0007493556],"genre_scores_gemma":[0.9954953,0.00005357848,0.002799595,0.001354156,0.0002426498,6.353511e-7,2.051611e-7,0.00001648928,0.00003744794],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.09699604,"threshold_uncertainty_score":0.4095964,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03429122021821501,"score_gpt":0.2901020471937479,"score_spread":0.2558108269755329,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}