{"id":"W3080840845","doi":"10.1101/2020.08.20.258822","title":"The Deubiquitylase Ubp15 Couples Transcription to mRNA Export","year":2020,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Nuclear Structure and Function","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval; Université de Montréal; Montreal Clinical Research Institute","funders":"Fonds de Recherche du Québec - Santé; Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; Fondation pour la Recherche Médicale","keywords":"Nuclear export signal; Messenger RNA; Ubiquitin ligase; Transcription (linguistics); Cell biology; RNA polymerase II; Nuclear pore; Ubiquitin; Biology; Nuclear transport; Cell nucleus; Gene expression; Genetics; Promoter; Gene; Nucleus","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001159694,0.0003254607,0.0001435307,0.0001429772,0.0001077692,0.0003759655,0.0001654845,0.0002004589,0.001271059],"category_scores_gemma":[0.00009421586,0.0001123751,0.0001763899,0.000120811,0.0002108644,0.0001592541,0.0002461568,0.0002252718,0.0006048754],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002660139,"about_ca_system_score_gemma":0.0001228861,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006675359,"about_ca_topic_score_gemma":0.0005643191,"domain_scores_codex":[0.9999301,0.0000085083,0.000005951988,0.00002559485,0.00001490064,0.00001490762],"domain_scores_gemma":[0.9999515,0.000006829888,0.00001278747,0.00001202518,0.000005340389,0.0000115838],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004664653,0.000006868431,0.0008391684,0.00002166823,0.000004710503,0.0001071164,0.000006120385,0.0001301924,0.9970868,0.000250717,0.00004979025,0.001450239],"study_design_scores_gemma":[0.000005797988,0.00002757695,0.003940681,0.000004281223,0.000005566838,0.0002038656,0.00001549539,0.001480051,0.9916324,0.0001731982,0.002508687,0.00000240623],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.986368,0.001916327,0.008630906,0.0001298053,0.00005299219,0.0000132813,0.0004999964,0.0001794326,0.002209345],"genre_scores_gemma":[0.9936964,0.0004920173,0.002429171,0.0000285837,0.000005409724,0.000004551032,0.0005574574,0.00001962258,0.002766676],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001271059,"threshold_uncertainty_score":0.004252136,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01255814498650089,"score_gpt":0.2146121050384627,"score_spread":0.2020539600519618,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}