{"id":"W3080841074","doi":"10.1016/j.virol.2020.08.003","title":"Cross protection by inactivated recombinant influenza viruses containing chimeric hemagglutinin conjugates with a conserved neuraminidase or M2 ectodomain epitope","year":2020,"lang":"en","type":"article","venue":"Virology","topic":"Influenza Virus Research Studies","field":"Medicine","cited_by":10,"is_retracted":false,"has_abstract":false,"ca_institutions":"Institute of Infection and Immunity","funders":"National Institute of Allergy and Infectious Diseases","keywords":"Epitope; Virology; Biology; Hemagglutinin (influenza); Recombinant DNA; Neuraminidase; Ectodomain; Influenza A virus; Virus; Antigenic drift; Antibody; Recombinant virus; H5N1 genetic structure; Gene; Genetics; Receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0003853954,0.0004261103,0.000968424,0.0001491602,0.0003709049,0.00006131711,0.0001896815,0.0002386076,0.0003403484],"category_scores_gemma":[0.002810985,0.0002966937,0.00008347128,0.0006903171,0.0007733965,0.0002078873,0.0001924916,0.0008472544,0.0001314225],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001176305,"about_ca_system_score_gemma":0.0003109017,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007642559,"about_ca_topic_score_gemma":0.00008005714,"domain_scores_codex":[0.9970059,0.0004586909,0.0006125467,0.00073078,0.0003497883,0.0008423136],"domain_scores_gemma":[0.9982152,0.0005130615,0.0003021986,0.0003412855,0.0002710859,0.0003571864],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.07078686,0.0004316922,0.05695804,0.0003347658,0.0006863169,0.00121226,0.001780271,0.00006398288,0.863466,0.00004470585,0.001184705,0.00305037],"study_design_scores_gemma":[0.04969036,0.06405079,0.150417,0.0004065063,0.0004278035,0.001309838,0.002055204,0.004628509,0.596743,0.00007772567,0.1285805,0.001612701],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.993435,0.0005577591,0.0001864664,0.003430596,0.00008825256,0.001717196,0.00003909524,0.0003274287,0.0002182482],"genre_scores_gemma":[0.9830589,0.00006576665,0.0002589205,0.01588597,0.0001003085,0.0004298661,0.00001834399,0.00007759914,0.0001043183],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.266723,"threshold_uncertainty_score":0.9999485,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1518862814875363,"score_gpt":0.380744849897995,"score_spread":0.2288585684104587,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}