{"id":"W3080973205","doi":"10.7554/elife.54693.sa2","title":"Author response: Senotherapeutic drugs for human intervertebral disc degeneration and low back pain","year":2020,"lang":"en","type":"peer-review","venue":"","topic":"Spine and Intervertebral Disc Pathology","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University Health Centre","funders":"","keywords":"Intervertebral disc; Cell biology; Senescence; Apoptosis; Biology; Bioinformatics; Medicine; Chemistry; Genetics; Anatomy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001134347,0.0008814256,0.0009506286,0.0009040207,0.0007730607,0.001936793,0.001529968,0.005298411,0.2883027],"category_scores_gemma":[0.004387849,0.0004183639,0.00101887,0.0006549849,0.0005156037,0.001346183,0.001000195,0.002823969,0.1154761],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001343373,"about_ca_system_score_gemma":0.001848314,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001410908,"about_ca_topic_score_gemma":0.003660041,"domain_scores_codex":[0.9988783,0.0001660046,0.0001229052,0.0001314293,0.0005347917,0.0001665687],"domain_scores_gemma":[0.997856,0.0005728176,0.0001928424,0.0001169543,0.0009126382,0.0003487815],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0002181738,0.00004030355,0.0001139443,0.0003144541,0.000008630273,0.0000829581,0.00001254667,0.00002912162,0.0005754931,0.0004175308,0.9681783,0.03000848],"study_design_scores_gemma":[0.0001699476,0.0001478644,0.0004790083,0.0001816406,0.00001382021,0.0001414714,0.00005517349,0.00005188743,0.001041099,0.0004453405,0.997261,0.00001176017],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.004783489,0.02767959,0.004217269,0.3546962,0.2454026,0.003032549,0.01979768,0.005133315,0.3352573],"genre_scores_gemma":[0.01029654,0.01486324,0.00346036,0.1112815,0.04161373,0.0009103163,0.00742126,0.0006354481,0.8095176],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.2883027,"threshold_uncertainty_score":0.9644685,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0766750476484071,"score_gpt":0.3842152680566953,"score_spread":0.3075402204082882,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}