{"id":"W3080984528","doi":"10.1016/j.apsb.2020.08.006","title":"Recent developments on PET radiotracers for TSPO and their applications in neuroimaging","year":2020,"lang":"en","type":"review","venue":"Acta Pharmaceutica Sinica B","topic":"Alzheimer's disease research and treatments","field":"Medicine","cited_by":176,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; Centre for Addiction and Mental Health","funders":"Applied Basic Research Foundation of Yunnan Province; K. C. Wong Education Foundation; National Natural Science Foundation of China","keywords":"Translocator protein; Neuroinflammation; Neuroscience; Positron emission tomography; Radioligand; Neuroimaging; Medicine; Context (archaeology); Psychology; Disease; Pathology; Receptor; Biology; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002132157,0.0009921606,0.001040025,0.001515049,0.0003082925,0.001601521,0.0009421253,0.002093635,0.002135733],"category_scores_gemma":[0.00166029,0.00078977,0.0007272422,0.001464732,0.0008705367,0.001745419,0.0007891283,0.002535738,0.001466449],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001007594,"about_ca_system_score_gemma":0.0009249406,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001505885,"about_ca_topic_score_gemma":0.001781157,"domain_scores_codex":[0.9994652,0.0001963323,0.00004322373,0.000119596,0.0001203314,0.00005528515],"domain_scores_gemma":[0.9989182,0.0006982326,0.0001033116,0.00003866875,0.0001909381,0.00005070639],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0008349724,0.000254814,0.001434099,0.01880717,0.0004420137,0.002277956,0.0003864651,0.0021231,0.1110714,0.01199696,0.02942599,0.8209451],"study_design_scores_gemma":[0.0001322075,0.001398688,0.003992572,0.002741096,0.0009714729,0.01499427,0.0002198429,0.003788064,0.07939985,0.007610139,0.8845392,0.000212509],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.002580384,0.9826921,0.009467515,0.001202229,0.0002316765,0.00003005367,0.00006763269,0.00008172232,0.003646658],"genre_scores_gemma":[0.02071674,0.9576794,0.01635272,0.001751218,0.0008100414,0.0001594722,0.0002505039,0.0000563481,0.002223543],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002135733,"threshold_uncertainty_score":0.01127607,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1799118344408047,"score_gpt":0.4668993606553656,"score_spread":0.2869875262145609,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}