{"id":"W3081335545","doi":"10.1039/d0sm01271h","title":"Anesthetics significantly increase the amount of intramembrane water in lipid membranes","year":2020,"lang":"en","type":"article","venue":"Soft Matter","topic":"Lipid Membrane Structure and Behavior","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"Natural Sciences and Engineering Research Council of Canada; Ontario Ministry of Research, Innovation and Science; Ontario Ministry of Economic Development and Innovation; Canada Foundation for Innovation; McMaster University","keywords":"Membrane; Lipid bilayer; Neutron diffraction; Chemistry; Molecular dynamics; Biophysics; Diffraction; Crystallography; Biochemistry; Computational chemistry; Biology; Physics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009014172,0.0002684427,0.0001652172,0.000141627,0.0001470841,0.00017614,0.0001621954,0.0002002361,0.0007749766],"category_scores_gemma":[0.0002045596,0.0001634594,0.0001965515,0.0001073498,0.0002590999,0.0003519116,0.0002752925,0.0003259653,0.0001165163],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002382878,"about_ca_system_score_gemma":0.0002149547,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001124062,"about_ca_topic_score_gemma":0.001261311,"domain_scores_codex":[0.9999348,0.000008414509,0.000004426369,0.00001424172,0.00001938469,0.00001875626],"domain_scores_gemma":[0.9999026,0.00003763434,0.00003459838,0.00000609277,0.000009289239,0.000009765752],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007382753,0.00001519236,0.0005545546,0.0000349548,0.00001114435,0.00004358459,0.00002224154,0.001172246,0.9963245,0.0002617475,0.00001811265,0.001467776],"study_design_scores_gemma":[0.00001955964,0.000168039,0.00444039,0.000007997656,0.00002251253,0.00007772978,0.00004118033,0.006309625,0.9876172,0.0003058303,0.000979993,0.00001007276],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9958439,0.001005531,0.00220518,0.00008708082,0.000008465357,0.000006560764,0.00006084807,0.00002483674,0.0007576572],"genre_scores_gemma":[0.996636,0.000982909,0.00188589,0.00003893885,0.000002217777,0.000009810622,0.00007972334,0.00001037757,0.0003541425],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001124062,"threshold_uncertainty_score":0.002592564,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008018307240589667,"score_gpt":0.216738920175157,"score_spread":0.2087206129345674,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}