{"id":"W3081417650","doi":"10.3390/cancers12092438","title":"Interaction of the Hippo Pathway and Phosphatases in Tumorigenesis","year":2020,"lang":"en","type":"review","venue":"Cancers","topic":"Hippo pathway signaling and YAP/TAZ","field":"Biochemistry, Genetics and Molecular Biology","cited_by":48,"is_retracted":false,"has_abstract":true,"ca_institutions":"Queen's University","funders":"Canadian Institutes of Health Research","keywords":"Hippo signaling pathway; Crosstalk; Kinase; Phosphorylation; Cell biology; Biology; Signal transduction; Carcinogenesis; Dephosphorylation; Phosphatase; Effector; Cancer; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000382958,0.0006978496,0.0007862879,0.00190238,0.0002619832,0.0007248596,0.0005080642,0.000767292,0.002246091],"category_scores_gemma":[0.0004295017,0.0002075266,0.0003556683,0.001903296,0.000411623,0.001046314,0.0006458908,0.001493875,0.001308198],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006356548,"about_ca_system_score_gemma":0.001016474,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007158083,"about_ca_topic_score_gemma":0.001313151,"domain_scores_codex":[0.9998724,0.00002148246,0.00001840475,0.00002320488,0.00004852564,0.0000159284],"domain_scores_gemma":[0.9998228,0.00006990832,0.0000261303,0.000005455705,0.00005217772,0.00002350547],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00009842608,0.00006096337,0.0003613044,0.01267247,0.00009326075,0.0004517692,0.00007305008,0.0004847895,0.004173587,0.005016107,0.03086925,0.945645],"study_design_scores_gemma":[0.00001143712,0.00008306222,0.001199042,0.001761779,0.00008703874,0.002275399,0.00004534464,0.0001204552,0.0009589482,0.002502326,0.9909378,0.00001737766],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001160284,0.9988018,0.00009772625,0.0002313413,0.0001456632,0.000001502422,0.000007746068,0.000005978635,0.0005921884],"genre_scores_gemma":[0.0006330558,0.9986601,0.0001028391,0.0001011256,0.000162475,0.000002195886,0.00001553827,8.41454e-7,0.000321832],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002246091,"threshold_uncertainty_score":0.007513881,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02725361396933928,"score_gpt":0.29327171138657,"score_spread":0.2660180974172308,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}