{"id":"W3081428374","doi":"10.1039/d0nr04100a","title":"Role of the complement cascade in the biological fate of liposomes in rodents","year":2020,"lang":"en","type":"article","venue":"Nanoscale","topic":"Nanoparticle-Based Drug Delivery","field":"Materials Science","cited_by":15,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval","funders":"Fundação de Apoio à Pesquisa, Universidade Federal de Goiás; Conselho Nacional de Desenvolvimento Científico e Tecnológico; Natural Sciences and Engineering Research Council of Canada; Fonds de Recherche du Québec - Santé; Financiadora de Estudos e Projetos; Coordenação de Aperfeiçoamento de Pessoal de Nível Superior","keywords":"Liposome; Complement (music); Cascade; Complement system; Circulation (fluid dynamics); Kinetics; Chemistry; Biophysics; Biology; Immunology; Biochemistry; Antibody; Physics; Chromatography","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002576021,0.0003324093,0.000179174,0.000654627,0.0001819295,0.0003838392,0.0001795619,0.0005699837,0.001967818],"category_scores_gemma":[0.0002183899,0.0001463464,0.000209953,0.0001056483,0.0003702853,0.0004883535,0.0001469778,0.0007567854,0.0002993357],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004585137,"about_ca_system_score_gemma":0.0002857342,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008590635,"about_ca_topic_score_gemma":0.0007579571,"domain_scores_codex":[0.9998752,0.00001977508,0.000007084717,0.00004255353,0.00001662715,0.00003889192],"domain_scores_gemma":[0.9998512,0.00003073451,0.00004037352,0.00002018055,0.00002092059,0.00003646397],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0009286379,0.000125714,0.0007609444,0.00005882856,0.000008757847,0.00008173248,0.00003932094,0.0001160885,0.9903101,0.000550664,0.0001029907,0.006916301],"study_design_scores_gemma":[0.00004082016,0.001391416,0.007080825,0.00001840174,0.00002499762,0.000315504,0.00004788312,0.001081364,0.9871132,0.0004893197,0.002383456,0.00001289502],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9847996,0.003545559,0.00779399,0.0002865171,0.00006062517,0.00006601965,0.0004545763,0.0001635592,0.002829478],"genre_scores_gemma":[0.9932652,0.0007373703,0.002855384,0.00006542155,0.00001176112,0.0000508377,0.0002172196,0.00002623818,0.002770585],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001967818,"threshold_uncertainty_score":0.006583035,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03064099011947337,"score_gpt":0.2577718845895134,"score_spread":0.2271308944700401,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}