{"id":"W3081505409","doi":"10.1007/978-1-0716-0664-3_14","title":"3D Immuno-DNA Fluorescence In Situ Hybridization (FISH) for Detection of HIV-1 and Cellular Genes in Primary CD4+ T Cells","year":2020,"lang":"en","type":"book-chapter","venue":"Methods in molecular biology","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":1,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Provirus; Fluorescence in situ hybridization; Genome; Chromatin; Biology; Fluorescence microscope; DNA; In situ; Computational biology; Chromosome conformation capture; In situ hybridization; Interphase; Gene; Chromosome; Genetics; Fluorescence; Chemistry; Gene expression","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002720646,0.000671084,0.0004172975,0.0007050285,0.0004128623,0.0006617305,0.0009241975,0.0008227477,0.01711985],"category_scores_gemma":[0.00008107812,0.0007379705,0.0006464793,0.0006569395,0.000472932,0.0006538741,0.0006408778,0.001297105,0.009524541],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00081066,"about_ca_system_score_gemma":0.0003163286,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001079588,"about_ca_topic_score_gemma":0.003167054,"domain_scores_codex":[0.9998481,0.00001656927,0.000006833528,0.00004144687,0.00006340219,0.00002362511],"domain_scores_gemma":[0.9999477,0.00002702268,0.000003368276,0.00000743998,0.000009664535,0.000004882358],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004284857,0.00002045048,0.00006357442,0.0003895512,0.000008926181,0.0001442507,0.00008050213,0.000718979,0.9272105,0.006899129,0.004450168,0.05997101],"study_design_scores_gemma":[0.00001388442,0.0001059686,0.000919092,0.00009856682,0.0000305728,0.001768652,0.00007479983,0.003958515,0.6364463,0.006521641,0.3500293,0.00003274686],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"methods","genre_gemma":"methods","genre_scores_codex":[0.03628858,0.03664643,0.7046333,0.00149213,0.001719572,0.0004589412,0.002781577,0.003841422,0.2121381],"genre_scores_gemma":[0.08880395,0.03649562,0.4761592,0.001262728,0.0002674219,0.0008704719,0.003115795,0.001231372,0.3917934],"genre_candidate":"methods","genre_consensus":"methods","teacher_disagreement_score":0.01711985,"threshold_uncertainty_score":0.0572716,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01680813047910726,"score_gpt":0.296620737448096,"score_spread":0.2798126069689887,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}