{"id":"W3081572286","doi":"10.1158/1557-3265.ovca19-b25","title":"Abstract B25: SMARCA4/BRG1 and AP-1 co-regulate an epithelial-like signature in small-cell carcinoma of ovary, hypercalcemic type (SCCOHT)","year":2020,"lang":"en","type":"article","venue":"Clinical Cancer Research","topic":"Chromatin Remodeling and Cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"","keywords":"SMARCA4; Biology; Carcinogenesis; Transcription factor; Chromatin immunoprecipitation; Gene; Cancer research; Chromatin remodeling; Molecular biology; Gene expression; Cell biology; Genetics; Promoter","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001029287,0.0002963109,0.0002259806,0.0003924587,0.0001762045,0.0002925199,0.0001930749,0.0002713548,0.002227637],"category_scores_gemma":[0.00009875678,0.0001646203,0.0002510319,0.0002326635,0.0002476181,0.0000854364,0.0002110625,0.0005085686,0.0006111932],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003151655,"about_ca_system_score_gemma":0.0001566376,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001049024,"about_ca_topic_score_gemma":0.001137149,"domain_scores_codex":[0.9998221,0.00001908386,0.00001519428,0.00003523321,0.0000661456,0.00004235273],"domain_scores_gemma":[0.9998696,0.00001505296,0.00003848349,0.00001679698,0.00001253005,0.00004755196],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.00005304678,0.00001722939,0.0004630398,0.00001223289,0.000003080225,0.0001134879,0.000007685601,0.00001319485,0.9990175,0.00003187422,0.00004050211,0.0002271565],"study_design_scores_gemma":[0.00004871935,0.0003574373,0.05319393,0.000006854687,0.00002869481,0.002022443,0.00009481049,0.0009335828,0.9394413,0.00005463431,0.003812708,0.000004857356],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9971552,0.0008161946,0.0007326854,0.0001047444,0.0000302377,0.00002229337,0.0004400869,0.00006218145,0.0006364079],"genre_scores_gemma":[0.99511,0.0002238327,0.0005788335,0.0000643886,0.000008266127,0.00003257794,0.0008779645,0.00001904754,0.003084984],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002227637,"threshold_uncertainty_score":0.00745219,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1448932915789845,"score_gpt":0.4363896479653528,"score_spread":0.2914963563863683,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}