{"id":"W3081800083","doi":"10.1002/sctm.19-0452","title":"Myogenic progenitor cells derived from human induced pluripotent stem cell are immune-tolerated in humanized mice","year":2020,"lang":"en","type":"article","venue":"Stem Cells Translational Medicine","topic":"Pluripotent Stem Cells Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":10,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; Centre Intégré Universitaire de Santé et de Services Sociaux du Centre-Sud-de-l'Île-de-Montréal; Centre hospitalier de l'Université Laval; Centre Hospitalier Universitaire Sainte-Justine","funders":"Fonds de Recherche du Québec - Santé; Canadian Institutes of Health Research","keywords":"Induced pluripotent stem cell; Reprogramming; Stem cell; Progenitor cell; Immune system; Immunology; Biology; Humanized mouse; Cell therapy; Adoptive cell transfer; Haematopoiesis; Cell biology; Peripheral blood mononuclear cell; Cancer research; T cell; Cell; In vitro; Embryonic stem cell","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001030248,0.0005172121,0.0004009872,0.0007248002,0.000185197,0.0006508912,0.000361633,0.0006966501,0.003367136],"category_scores_gemma":[0.0003411087,0.0003168345,0.0003804965,0.000183899,0.0005104046,0.0004019726,0.0003295122,0.001205607,0.0006955121],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001620127,"about_ca_system_score_gemma":0.0002428262,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001930222,"about_ca_topic_score_gemma":0.0002399347,"domain_scores_codex":[0.9993719,0.0001370493,0.00007508842,0.0001681071,0.000165576,0.00008232548],"domain_scores_gemma":[0.9996493,0.00007033027,0.0001254104,0.0000717625,0.00002830022,0.00005503261],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002246893,0.0001095574,0.0001747447,0.00006326771,0.00001466107,0.0001221686,0.00005068987,0.00009559027,0.9956087,0.0004747824,0.0001173013,0.002943787],"study_design_scores_gemma":[0.000094087,0.001987803,0.003221561,0.00004667449,0.00006579202,0.00133605,0.00005807432,0.001542012,0.9814565,0.0003281404,0.00985101,0.00001233103],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.955703,0.003561434,0.03290908,0.0004275427,0.0002010509,0.0003748909,0.00108996,0.0007833201,0.004949782],"genre_scores_gemma":[0.9761714,0.00219965,0.01070946,0.0003050484,0.00004689925,0.0004367609,0.001379738,0.0001583855,0.00859272],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003367136,"threshold_uncertainty_score":0.01126415,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03437729868321516,"score_gpt":0.2628285921280805,"score_spread":0.2284512934448653,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}