{"id":"W3081800083","doi":"10.1002/sctm.19-0452","title":"Myogenic progenitor cells derived from human induced pluripotent stem cell are immune-tolerated in humanized mice","year":2020,"lang":"en","type":"article","venue":"Stem Cells Translational Medicine","topic":"Pluripotent Stem Cells Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":10,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; Centre Intégré Universitaire de Santé et de Services Sociaux du Centre-Sud-de-l'Île-de-Montréal; Centre hospitalier de l'Université Laval; Centre Hospitalier Universitaire Sainte-Justine","funders":"Fonds de Recherche du Québec - Santé; Canadian Institutes of Health Research","keywords":"Induced pluripotent stem cell; Reprogramming; Stem cell; Progenitor cell; Immune system; Immunology; Biology; Humanized mouse; Cell therapy; Adoptive cell transfer; Haematopoiesis; Cell biology; Peripheral blood mononuclear cell; Cancer research; T cell; Cell; In vitro; Embryonic stem cell","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0003072527,0.0004910337,0.000664849,0.0001511522,0.0001696541,0.00003223949,0.0005924015,0.0003710836,0.0002610547],"category_scores_gemma":[0.000006175798,0.0004671443,0.0001932537,0.0004226658,0.0001549427,0.00001655999,0.0001024683,0.0004695129,0.0001027628],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005374596,"about_ca_system_score_gemma":0.0001997987,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000172045,"about_ca_topic_score_gemma":0.0001109792,"domain_scores_codex":[0.9960979,0.0003683433,0.001063701,0.001028128,0.0008356521,0.0006062501],"domain_scores_gemma":[0.9985343,0.00007766029,0.0003188007,0.0004303953,0.0002476146,0.0003912444],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004598347,0.0001635722,0.0008578163,0.0001573244,0.000123104,0.00007481316,0.0007132686,0.0002574676,0.9962654,0.000003468013,0.0003093142,0.0006146053],"study_design_scores_gemma":[0.005936117,0.0005040318,0.003314019,0.0001386768,0.00006913712,0.00000322216,0.0007586228,0.0006347496,0.9864136,0.00001159627,0.001751872,0.0004643503],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9920048,0.003711308,0.00041129,0.001738567,0.000307156,0.001250289,0.0001489352,0.00004963863,0.0003780836],"genre_scores_gemma":[0.9972228,0.00015366,0.000181979,0.000474436,0.0006764022,0.0000778299,0.0007005334,0.00009048254,0.0004218274],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.009851807,"threshold_uncertainty_score":0.999778,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03437729868321516,"score_gpt":0.2628285921280805,"score_spread":0.2284512934448653,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}