{"id":"W3081911417","doi":"10.1158/1538-7445.am2020-ct288","title":"Abstract CT288: Phase 3, randomized, placebo-controlled study of stereotactic body radiotherapy (SBRT) with or without pembrolizumab in patients with inoperable stage I/IIA non-small-cell lung cancer (NSCLC): KEYNOTE-867","year":2020,"lang":"en","type":"article","venue":"Cancer Research","topic":"Lung Cancer Diagnosis and Treatment","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Kingston General Hospital","funders":"","keywords":"Medicine; Pembrolizumab; Clinical endpoint; Internal medicine; Oncology; Placebo; Lung cancer; Stage (stratigraphy); non-small cell lung cancer (NSCLC); Radiation therapy; Cancer; Randomized controlled trial; Pathology; Immunotherapy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001481744,0.002239406,0.002398419,0.0004232119,0.0006111492,0.001066713,0.001175729,0.001697738,0.01382713],"category_scores_gemma":[0.00151915,0.0006733987,0.001449552,0.0004610184,0.001281793,0.0009860665,0.0003554148,0.003808717,0.00208465],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007309341,"about_ca_system_score_gemma":0.001949301,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00134307,"about_ca_topic_score_gemma":0.004098407,"domain_scores_codex":[0.9996165,0.0001957884,0.0000247903,0.0000785083,0.00003504302,0.00004938051],"domain_scores_gemma":[0.9993718,0.0001285092,0.0001601636,0.00004528866,0.00005959899,0.0002346767],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.972997,0.008248846,0.0003727759,0.0008329157,0.000551526,0.00004683084,0.00004672329,0.0003099624,0.006843447,0.0001542243,0.002052115,0.00754358],"study_design_scores_gemma":[0.9595702,0.03846821,0.0005833943,0.00002392097,0.0001794555,0.00002157584,0.00001028017,0.0002130225,0.0003285716,0.00008623856,0.0005072975,0.000007772846],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9527724,0.004936864,0.001833228,0.001484278,0.001072265,0.02379188,0.006048516,0.0006092264,0.007451236],"genre_scores_gemma":[0.9558324,0.003013885,0.003714242,0.002868364,0.0006310283,0.02002314,0.004321468,0.00008427502,0.009511294],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01382713,"threshold_uncertainty_score":0.0462563,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03283083314242326,"score_gpt":0.3822844894949869,"score_spread":0.3494536563525637,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}