{"id":"W3082003040","doi":"10.1158/1557-3265.ovca19-a61","title":"Abstract A61: FAK activity sustains intrinsic and acquired ovarian cancer resistance to platinum chemotherapy","year":2020,"lang":"en","type":"article","venue":"Clinical Cancer Research","topic":"Cancer, Lipids, and Metabolism","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Cancer research; Ovarian cancer; Cisplatin; Wnt signaling pathway; Cancer; Cancer cell; KRAS; Chemotherapy; Biology; Signal transduction; Medicine; Internal medicine; Cell biology; Colorectal cancer","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00005613495,0.0001566774,0.0001776679,0.000259055,0.0001577007,0.0003059107,0.00007515677,0.0001691356,0.001634986],"category_scores_gemma":[0.000101899,0.00008391438,0.0001409591,0.0001863409,0.0001316912,0.00009707319,0.0001685648,0.0002848442,0.0002710621],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000245757,"about_ca_system_score_gemma":0.0001530063,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004352684,"about_ca_topic_score_gemma":0.0006145083,"domain_scores_codex":[0.999908,0.000005164556,0.000007658999,0.00002373128,0.00003389194,0.00002165414],"domain_scores_gemma":[0.9999316,0.000007636394,0.00002623966,0.000008747049,0.000007691297,0.00001803909],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000153747,0.00001524152,0.002657822,0.00001708754,0.000004648378,0.0001028885,0.00001250978,0.00004559712,0.9944324,0.0000722991,0.00008547765,0.002400245],"study_design_scores_gemma":[0.0000370953,0.0006079398,0.1334665,0.00001252945,0.00005112414,0.001501647,0.0001431482,0.002316439,0.857511,0.0001989677,0.004141879,0.00001176704],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9984092,0.0002411416,0.0003470343,0.00004885209,0.00001171064,0.000007727142,0.0004086413,0.00002704595,0.0004987444],"genre_scores_gemma":[0.9970397,0.000166109,0.0002948878,0.00003176813,0.000005525225,0.00001113481,0.0006290094,0.000009444648,0.0018124],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001634986,"threshold_uncertainty_score":0.005469561,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1091765480890419,"score_gpt":0.452831612145723,"score_spread":0.3436550640566811,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}