{"id":"W3082009283","doi":"10.1158/1557-3265.ovca19-a29","title":"Abstract A29: Anticancer effects of polo-like kinase-4 inhibitor (CFI-400945) in ovarian cancer","year":2020,"lang":"en","type":"article","venue":"Clinical Cancer Research","topic":"Microtubule and mitosis dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"","keywords":"Ovarian cancer; Biology; Cell cycle; Cancer research; Cancer; Mitosis; Carcinogenesis; Propidium iodide; Cell growth; Viability assay; Mitotic catastrophe; BUB1; Cancer cell; Molecular biology; Cell; Apoptosis; Cell biology; Programmed cell death; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001060544,0.0002782805,0.0003045146,0.0004381438,0.000142419,0.0001459711,0.0001547901,0.000252135,0.003531509],"category_scores_gemma":[0.0001041879,0.00007827216,0.000219165,0.0002981275,0.0001004753,0.0001238763,0.0001188902,0.0004450228,0.0003453676],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000182865,"about_ca_system_score_gemma":0.0002639722,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009321563,"about_ca_topic_score_gemma":0.0007979548,"domain_scores_codex":[0.9999498,0.000007878936,0.000006832072,0.00000991755,0.00001385455,0.00001182199],"domain_scores_gemma":[0.9999436,0.00001451499,0.00000960642,0.000005377429,0.00001021005,0.00001656267],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002239278,0.0006534529,0.001213346,0.0003840036,0.00003998776,0.0003180254,0.00003443629,0.0004714915,0.968592,0.0001183902,0.0008325726,0.025103],"study_design_scores_gemma":[0.0004570019,0.008478642,0.01712539,0.0000284864,0.0001113258,0.0009221952,0.00005257128,0.001501227,0.9616252,0.00008678896,0.009599588,0.00001157667],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9888955,0.005542885,0.0006626633,0.0001904002,0.00007412533,0.0001106136,0.001106803,0.0001162184,0.003300656],"genre_scores_gemma":[0.9911049,0.002183544,0.001076279,0.0001185727,0.00002228084,0.00006441287,0.00161236,0.00001270783,0.003804837],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003531509,"threshold_uncertainty_score":0.01181412,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08396940545288109,"score_gpt":0.4509874401042446,"score_spread":0.3670180346513635,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}