{"id":"W3082118485","doi":"10.1053/j.gastro.2020.06.097","title":"Nucleic Acid Polymer Therapy for Hepatitis B Virus: Strong Hepatitis B Surface Antigen Decline But Many Unanswered Questions","year":2020,"lang":"en","type":"letter","venue":"Gastroenterology","topic":"Hepatitis B Virus Studies","field":"Medicine","cited_by":4,"is_retracted":false,"has_abstract":false,"ca_institutions":"Toronto Liver Centre; University Health Network","funders":"Janssen Pharmaceuticals; Gilead Sciences; Fujirebio Europe; British Microcirculation Society; Janssen Biotech; Roche; GlaxoSmithKline","keywords":"HBsAg; Hepatitis B virus; Hepatitis B; Medicine; Seroconversion; Antigen; Virology; Immunology; Antibody; Internal medicine; Virus","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003631177,0.0006642346,0.001302288,0.000671256,0.0034088,0.003138692,0.001376729,0.04522081,0.005593923],"category_scores_gemma":[0.01793461,0.0005001521,0.0008232127,0.0007120228,0.004139305,0.004110148,0.001512856,0.02292133,0.003488551],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00385696,"about_ca_system_score_gemma":0.004223013,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.004124294,"about_ca_topic_score_gemma":0.008245591,"domain_scores_codex":[0.9972888,0.00137278,0.000338437,0.0001819572,0.000477401,0.0003405563],"domain_scores_gemma":[0.9895861,0.006351156,0.0005512712,0.0002866494,0.00108226,0.002142613],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0002641421,0.0001539899,0.003938168,0.0001319066,0.00004017889,0.009766596,0.0002231608,0.0001105752,0.0005510115,0.007129775,0.9484454,0.02924515],"study_design_scores_gemma":[0.0005121845,0.0003769134,0.004664967,0.0008090842,0.00007590447,0.01057218,0.0009763379,0.0006415446,0.0005544043,0.02846125,0.9522499,0.0001052393],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.0007383125,0.001922225,0.00006383457,0.9863368,0.007608496,0.000007377867,0.00002184527,0.000009312917,0.00329179],"genre_scores_gemma":[0.009172318,0.002841903,0.0003452464,0.9281166,0.05182566,0.00003275203,0.00003952598,0.00002295042,0.007603176],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.04522081,"threshold_uncertainty_score":0.02798432,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02597436658737724,"score_gpt":0.2796896601277298,"score_spread":0.2537152935403525,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}