{"id":"W3082236720","doi":"10.1101/2020.09.01.278952","title":"Structural Variants in SARS-CoV-2 Occur at Template-Switching Hotspots","year":2020,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"SARS-CoV-2 and COVID-19 Research","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"Stanford Bio-X; National Science Foundation","keywords":"Biology; Genetics; Indel; Recombination; RNA; Evolutionary biology; Genome; Gene conversion; RNA polymerase; Computational biology; Gene; Single-nucleotide polymorphism; Genotype","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002626169,0.0002319581,0.0004003847,0.0008272345,0.0003316642,0.0005364867,0.0001966278,0.0004465162,0.001651641],"category_scores_gemma":[0.0006432312,0.0001994494,0.0004953808,0.001067584,0.0002373871,0.0003004267,0.0002980738,0.000413427,0.0006661539],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002344097,"about_ca_system_score_gemma":0.0001490765,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008713711,"about_ca_topic_score_gemma":0.001394701,"domain_scores_codex":[0.999579,0.0000387279,0.0000350431,0.0001577389,0.0001173836,0.0000721362],"domain_scores_gemma":[0.9993615,0.0001014995,0.0002860059,0.00007667354,0.00009815396,0.00007613899],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0008293314,0.0000882415,0.2300469,0.0002518611,0.0001714163,0.001151456,0.0005264324,0.001095008,0.7533293,0.0005826273,0.0005439622,0.01138345],"study_design_scores_gemma":[0.00002967905,0.0002682457,0.9245357,0.00004291223,0.0001170483,0.002629115,0.0005650128,0.00275176,0.06293005,0.0006695691,0.005418865,0.0000420282],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9963301,0.0005673867,0.001061654,0.00002634833,0.0000119075,0.00001396226,0.001163637,0.00005923784,0.0007658694],"genre_scores_gemma":[0.9958274,0.00008259288,0.001241508,0.00004270967,0.00001358158,0.000007850742,0.002534424,0.00001879044,0.0002310978],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001651641,"threshold_uncertainty_score":0.005525291,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05200807416162519,"score_gpt":0.3112120199939263,"score_spread":0.2592039458323011,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}