{"id":"W3082248576","doi":"10.1016/j.aca.2020.08.030","title":"Applications of gold nanoparticles in ELISA, PCR, and immuno-PCR assays: A review","year":2020,"lang":"en","type":"review","venue":"Analytica Chimica Acta","topic":"Advanced biosensing and bioanalysis techniques","field":"Biochemistry, Genetics and Molecular Biology","cited_by":173,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Prince Edward Island","funders":"Mitacs","keywords":"Chemistry; Detection limit; Colloidal gold; Analyte; Immunoassay; Nucleic acid; Polymerase chain reaction; Aptamer; Nanotechnology; Molecular biology; Chromatography; Nanoparticle; Antibody; Biochemistry; Biology; Immunology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002405263,0.0003487288,0.00140005,0.0001175754,0.00002791442,0.00001730263,0.0003393251,0.0002700332,0.000002737529],"category_scores_gemma":[0.0001748477,0.0002792075,0.0004108082,0.0005839466,0.0001661865,0.000004309522,0.0002276876,0.0002339357,0.000003871883],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002618569,"about_ca_system_score_gemma":0.0001247462,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000053574,"about_ca_topic_score_gemma":0.00001619046,"domain_scores_codex":[0.9981192,0.0001331931,0.000786995,0.0005978413,0.0001373365,0.0002253898],"domain_scores_gemma":[0.9986873,0.00004737398,0.0004298994,0.0006766536,0.00007373039,0.00008502997],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0000140615,0.0001863742,0.00001158474,0.01642441,0.0006163138,0.000005460208,0.000008613442,5.765535e-9,0.04234613,0.0001005924,0.005225157,0.9350613],"study_design_scores_gemma":[0.00007177387,0.00006462571,0.000001964502,0.006526465,0.001140616,0.00001981732,0.000005413255,0.000005779533,0.003731442,0.00004383318,0.9880849,0.0003033605],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00005292023,0.9983822,0.00001198549,0.0002791054,0.000007232459,0.0006014685,0.00007303017,0.00002089964,0.0005711605],"genre_scores_gemma":[0.003933717,0.9942255,0.001007214,0.0002307648,0.00006673732,0.00007499997,0.000302442,0.00003506027,0.0001235886],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9828597,"threshold_uncertainty_score":0.999966,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01955022059949176,"score_gpt":0.3177139021698914,"score_spread":0.2981636815703996,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}