{"id":"W3082257154","doi":"10.18433/jpps31424","title":"Biowaiver for Immediate and Modified Release Dosage forms Scientific summary of the CSPS workshop","year":2020,"lang":"en","type":"article","venue":"Journal of Pharmacy & Pharmaceutical Sciences","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"","keywords":"Dosage form; Bioequivalence; Immediate release; Active ingredient; Medicine; Pharmacology; Bioavailability","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":true,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001135323,0.00009904879,0.000143209,0.00003258709,0.0002219826,0.00005969219,0.0004968444,0.00003515171,0.00002514082],"category_scores_gemma":[0.0004939861,0.00005922121,0.000151099,0.0002820056,0.000970841,0.00003024101,0.0001373158,0.0001516499,5.744113e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000008896995,"about_ca_system_score_gemma":0.0002041059,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000001133292,"about_ca_topic_score_gemma":7.868127e-7,"domain_scores_codex":[0.9987655,0.00009204297,0.0003771835,0.0002384049,0.000319282,0.0002076169],"domain_scores_gemma":[0.9991584,0.00007069139,0.0002413459,0.0001053626,0.0001694934,0.0002547261],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005405549,0.0001066596,0.004456593,0.00007016213,0.00003161699,0.00000126002,0.0001588039,0.00009109773,0.9568536,0.000398847,0.001122284,0.03616847],"study_design_scores_gemma":[0.001857869,0.0001550077,0.0009085029,0.00001759985,0.00006248655,0.00001085088,0.0001214212,0.007477077,0.7969369,0.0003889463,0.1919359,0.0001274751],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9802698,0.006644043,0.001636631,0.01055216,0.0003546985,0.0003397806,0.00003325664,0.000003457865,0.0001661185],"genre_scores_gemma":[0.9980539,0.0004995611,0.0004067064,0.0008358631,0.0001410838,0.000005026621,0.000001821189,0.000004635146,0.00005138373],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1908136,"threshold_uncertainty_score":0.3577104,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08292671490511838,"score_gpt":0.3711271928273344,"score_spread":0.288200477922216,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}