{"id":"W3082363863","doi":"10.3389/fneur.2020.00784","title":"Multiple Sclerosis as a Syndrome—Implications for Future Management","year":2020,"lang":"en","type":"article","venue":"Frontiers in Neurology","topic":"Phagocytosis and Immune Regulation","field":"Immunology and Microbiology","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Montreal Neurological Institute and Hospital","funders":"Multiple Sclerosis Australia; National Institute of Neurological Disorders and Stroke; Medical Research Council; National Health and Medical Research Council; State Government of Victoria; Australian Government; Strong","keywords":"Multiple sclerosis; Neuroscience; MERTK; Phenocopy; Disease; Immune system; Biology; Computational biology; Medicine; Immunology; Phenotype; Genetics; Gene; Pathology; Receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003251221,0.0007455077,0.001557873,0.001352508,0.00140959,0.002159193,0.00178223,0.006753663,0.004286573],"category_scores_gemma":[0.006888757,0.0002907249,0.0006119979,0.0005465228,0.002482999,0.005169604,0.001999307,0.007537336,0.001019089],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002034527,"about_ca_system_score_gemma":0.005012457,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001940023,"about_ca_topic_score_gemma":0.002893426,"domain_scores_codex":[0.9988053,0.0004337978,0.000198655,0.0001543181,0.0002951453,0.0001128737],"domain_scores_gemma":[0.9969115,0.001093974,0.0002775414,0.0001227485,0.0006786532,0.0009155927],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"theoretical_or_conceptual","study_design_scores_codex":[0.0004210117,0.0006803398,0.01313543,0.001864747,0.0001599952,0.0236611,0.001132369,0.002610171,0.002614307,0.1081415,0.2503041,0.5952749],"study_design_scores_gemma":[0.0002254981,0.0006830523,0.01331595,0.00950441,0.0002945749,0.06012154,0.006458439,0.00480459,0.0003937977,0.3267707,0.5771296,0.0002979054],"study_design_candidate":"theoretical_or_conceptual","study_design_consensus":null,"genre_codex":"commentary","genre_gemma":"empirical","genre_scores_codex":[0.004787813,0.2300638,0.00546544,0.7370107,0.01058354,0.00004998576,0.0001071315,0.0001415212,0.01179006],"genre_scores_gemma":[0.1453088,0.5348088,0.02953433,0.1567822,0.1202101,0.0004402746,0.000647896,0.00008594376,0.01218156],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.006753663,"threshold_uncertainty_score":0.01719433,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02430382891886136,"score_gpt":0.2203753756991387,"score_spread":0.1960715467802773,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}