{"id":"W3082493289","doi":"10.1186/s13041-020-00663-9","title":"Cav3.2 T-type calcium channels control acute itch in mice","year":2020,"lang":"en","type":"article","venue":"Molecular Brain","topic":"Dermatology and Skin Diseases","field":"Medicine","cited_by":23,"is_retracted":false,"has_abstract":true,"ca_institutions":"Alberta Children's Hospital; University of Calgary","funders":"National Institute of Arthritis and Musculoskeletal and Skin Diseases; National Institute of Neurological Disorders and Stroke; National Institute of General Medical Sciences; National Institutes of Health; Canadian Institutes of Health Research; Alberta Innovates","keywords":"Scratching; Histamine; Voltage-dependent calcium channel; Pharmacology; Nociception; Medicine; Chloroquine; Calcium channel; Calcium; Internal medicine; Immunology; Receptor","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007041259,0.0001292468,0.0002978271,0.00005776839,0.00002345614,0.000009511968,0.00009742072,0.0001125851,0.0001105451],"category_scores_gemma":[0.000359506,0.000124251,0.00008552783,0.0002402597,0.00004982349,0.00003036961,0.00002908397,0.0001859441,0.0001983994],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001627238,"about_ca_system_score_gemma":0.0000862512,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001471381,"about_ca_topic_score_gemma":0.000001900147,"domain_scores_codex":[0.9990796,0.00009866908,0.0001772572,0.0002503896,0.0001383276,0.0002557992],"domain_scores_gemma":[0.9995018,0.00005373083,0.00003055972,0.000154442,0.00004175603,0.0002176887],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001412337,0.0003006572,0.03274989,0.0001830675,0.0004724158,0.02399697,0.0009914581,0.0001351634,0.7814909,0.0004922932,0.1571213,0.0006535798],"study_design_scores_gemma":[0.04496626,0.001070509,0.07685912,0.0004592707,0.001561972,0.00200458,0.0005877461,0.02475874,0.7733592,0.001646806,0.07075286,0.001972942],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9106168,0.001247498,0.002499492,0.08304571,0.0001613958,0.0004127443,0.00001473163,0.00008253824,0.001919133],"genre_scores_gemma":[0.9362233,0.000004394151,0.00007611858,0.06334317,0.00006007785,0.00001538426,0.00003657459,0.00002042969,0.0002205985],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.08636846,"threshold_uncertainty_score":0.506681,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01437542361003007,"score_gpt":0.2816091988138321,"score_spread":0.267233775203802,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}