{"id":"W3082645444","doi":"10.3390/biom10091263","title":"Lipid Phosphate Phosphatases and Cancer","year":2020,"lang":"en","type":"review","venue":"Biomolecules","topic":"Sphingolipid Metabolism and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":51,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"Canadian Cancer Society Research Institute; Canadian Institutes of Health Research","keywords":"Phosphatase; Extracellular; Endoplasmic reticulum; Sphingolipid; Intracellular; Golgi apparatus; Cell biology; Sphingosine; Sphingosine-1-phosphate; Phosphate; Chemistry; Phospholipid; Signal transduction; Phosphorylation; Cell signaling; Cancer cell; Phospholipase D; Cancer; Biochemistry; Membrane; Biology; Receptor","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00008911374,0.000471851,0.0009156275,0.00005584836,0.00008410494,0.00007520021,0.0002986282,0.0003189967,0.00003160832],"category_scores_gemma":[0.00007787826,0.0003930128,0.0003003596,0.0001660191,0.0001510453,0.000002419286,0.0002736893,0.0001326616,0.00002508907],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001056575,"about_ca_system_score_gemma":0.0002305794,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00006767798,"about_ca_topic_score_gemma":0.000008460027,"domain_scores_codex":[0.9984095,0.00008029892,0.0003601903,0.000705216,0.000133445,0.0003113643],"domain_scores_gemma":[0.9992052,0.00001672597,0.0002104738,0.0003314048,0.00003633047,0.0001998376],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00001177696,0.00001515538,0.00000272312,0.002149086,0.0001980685,0.00001765908,0.0000123737,1.285578e-7,0.001125474,0.0001061111,0.00191587,0.9944456],"study_design_scores_gemma":[0.0001954218,0.00004723152,8.089647e-7,0.001159951,0.0004781453,0.00003011623,0.000009578941,0.000001565403,0.005876686,0.000003733192,0.9917457,0.0004510473],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00003981351,0.998467,0.0001165273,0.00004097373,0.0004350161,0.0003231287,0.0004481858,0.00002883086,0.0001005581],"genre_scores_gemma":[0.00002941269,0.9971345,0.0002983798,0.0002730101,0.001326412,0.0001157548,0.0005920356,0.0000868658,0.000143621],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9939945,"threshold_uncertainty_score":0.9998522,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02811053582517651,"score_gpt":0.3199828680380853,"score_spread":0.2918723322129088,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}