{"id":"W3082667220","doi":"10.1101/2020.09.02.280529","title":"Mutation in position of 32 (G>U) of S2M differentiate human SARS-CoV2 from Bat Coronavirus","year":2020,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"SARS-CoV-2 and COVID-19 Research","field":"Medicine","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"","keywords":"Biology; Genetics; Coronavirus; Peptide sequence; Conserved sequence; Computational biology; RNA; Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2); Walker motifs; Mutation; Virology; Sequence alignment; Gene; Coronavirus disease 2019 (COVID-19); Enzyme; ATPase; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001853061,0.0005054166,0.0004043899,0.0003143846,0.000288013,0.000253029,0.0001393223,0.0007024833,0.003156479],"category_scores_gemma":[0.0003382637,0.0001579147,0.0006403158,0.000259848,0.0003856073,0.00018223,0.000295796,0.0004624208,0.00117509],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002177858,"about_ca_system_score_gemma":0.0002908494,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007639268,"about_ca_topic_score_gemma":0.001393962,"domain_scores_codex":[0.9997814,0.00007184211,0.00002996916,0.00004741622,0.00003527299,0.00003415022],"domain_scores_gemma":[0.9998074,0.00003696335,0.00006056901,0.00002258133,0.00001783525,0.00005467995],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001058538,0.0001044533,0.00881147,0.0001283377,0.00006610925,0.003927115,0.0001668039,0.0006245438,0.978072,0.0007000621,0.0004705761,0.005869906],"study_design_scores_gemma":[0.0003363716,0.003412618,0.1054278,0.0001894145,0.0003106829,0.02333694,0.0006189719,0.008899419,0.8337233,0.001301157,0.02230995,0.0001333507],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9953436,0.0005695163,0.001888665,0.0001552169,0.000123095,0.00005378618,0.0004564271,0.00007225522,0.001337433],"genre_scores_gemma":[0.9965931,0.0001083769,0.001511459,0.0001267239,0.00002304881,0.00002944226,0.0004690079,0.000030658,0.001108174],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003156479,"threshold_uncertainty_score":0.0105595,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04875537554828405,"score_gpt":0.3160327697673868,"score_spread":0.2672773942191028,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}