{"id":"W3082712996","doi":"10.3390/pharmaceutics12090824","title":"Pharmacokinetics of Shikimic Acid Following Intragastric and Intravenous Administrations in Rats","year":2020,"lang":"en","type":"article","venue":"Pharmaceutics","topic":"Antibiotics Pharmacokinetics and Efficacy","field":"Medicine","cited_by":12,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"National Research Foundation of Korea","keywords":"Shikimic acid; Pharmacokinetics; Chemistry; Chromatography; Bioavailability; Pharmacology; Clearance; Half-life; Pharmacodynamics; Biochemistry; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001494537,0.0001972174,0.0003743341,0.0001306582,0.00003949494,0.00001839687,0.0001103384,0.00007000317,0.00007400379],"category_scores_gemma":[0.0000954846,0.0002031457,0.00008718707,0.0005118528,0.00009240539,0.00005408184,0.0000742154,0.0004247191,0.000009532068],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002548532,"about_ca_system_score_gemma":0.0001375683,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000003245252,"about_ca_topic_score_gemma":8.436061e-7,"domain_scores_codex":[0.9986521,0.00003994927,0.0004829767,0.0002714765,0.000244158,0.0003093176],"domain_scores_gemma":[0.9992796,0.00006705029,0.0001012054,0.0001209919,0.00005944097,0.0003717009],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004063984,0.0005921687,0.02337068,0.0005304352,0.0002010672,0.0003992441,0.001768802,0.0002762766,0.9446437,0.0002863763,0.0004546898,0.02707016],"study_design_scores_gemma":[0.008058835,0.0008039512,0.01442746,0.0001558208,0.001078014,0.0001131004,0.000363839,0.08411424,0.8807763,0.00006361937,0.009581621,0.0004631907],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9915656,0.001377407,0.0009994775,0.00441158,0.0001799697,0.0004613306,0.00002453803,0.00004583646,0.0009342604],"genre_scores_gemma":[0.9941145,0.001486972,0.002266917,0.001883835,0.0001730868,0.000002681307,0.00002260966,0.00003328453,0.00001617603],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.08383796,"threshold_uncertainty_score":0.8284041,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06033900438429408,"score_gpt":0.3518107346251636,"score_spread":0.2914717302408695,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}