{"id":"W3082793371","doi":"10.1021/acs.jafc.0c02555","title":"<i>Sargassum fusiforme</i> Fucoidan Alleviates High-Fat Diet-Induced Obesity and Insulin Resistance Associated with the Improvement of Hepatic Oxidative Stress and Gut Microbiota Profile","year":2020,"lang":"en","type":"article","venue":"Journal of Agricultural and Food Chemistry","topic":"Gut microbiota and health","field":"Biochemistry, Genetics and Molecular Biology","cited_by":91,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Northern British Columbia","funders":"Wenzhou Municipal Science and Technology Bureau; Ministry of Science and Technology of the People's Republic of China; Natural Science Foundation of Zhejiang Province; National Natural Science Foundation of China","keywords":"Fucoidan; Insulin resistance; Oxidative stress; Gut flora; Endocrinology; Inflammation; Internal medicine; Antioxidant; Type 2 diabetes; Biology; Chemistry; Insulin; Diabetes mellitus; Biochemistry; Polysaccharide; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009290801,0.0003997577,0.0003240825,0.0003658414,0.000180469,0.0001665181,0.0001313631,0.0002001046,0.0010924],"category_scores_gemma":[0.00006439682,0.00008038151,0.0002591578,0.0001982517,0.0001675198,0.0002868956,0.0001732559,0.0005099555,0.00009086268],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001758934,"about_ca_system_score_gemma":0.0002188497,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001009536,"about_ca_topic_score_gemma":0.001351747,"domain_scores_codex":[0.9999503,0.000008992052,0.000004175882,0.000007956646,0.00001083666,0.00001776603],"domain_scores_gemma":[0.9999608,0.000002018963,0.00001585887,0.000002484712,0.000005337308,0.00001351806],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.001974338,0.0002831416,0.0005367954,0.0002156459,0.00004198462,0.0001034616,0.00001850551,0.0001351929,0.9851031,0.0001972899,0.0001682012,0.01122233],"study_design_scores_gemma":[0.0001917199,0.004926456,0.02742417,0.0000611628,0.0001639814,0.0005940386,0.0001151409,0.001557158,0.9549019,0.0003993806,0.009641596,0.00002332725],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9939261,0.002593083,0.001575102,0.0002304677,0.00004476294,0.0000265988,0.0002503789,0.00008064301,0.001272794],"genre_scores_gemma":[0.9958087,0.001154632,0.001320509,0.0001461352,0.00001697915,0.0000176124,0.0002770721,0.00000974337,0.001248604],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0010924,"threshold_uncertainty_score":0.00365448,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005824578290281447,"score_gpt":0.1853684444201158,"score_spread":0.1795438661298344,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}