{"id":"W3082868024","doi":"10.3390/biom10091253","title":"The Morphoregulatory Role of Thidiazuron: Metabolomics-Guided Hypothesis Generation for Mechanisms of Activity","year":2020,"lang":"en","type":"article","venue":"Biomolecules","topic":"Plant tissue culture and regeneration","field":"Biochemistry, Genetics and Molecular Biology","cited_by":58,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Guelph; University of British Columbia, Okanagan Campus; University of British Columbia","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Metabolomics; Metabolism; Thidiazuron; Biochemistry; Phenylpropanoid; Metabolome; Metabolic pathway; Chemistry; Organogenesis; Metabolite; Secondary metabolism; Biology; Tissue culture; Biosynthesis; In vitro; Bioinformatics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001010851,0.00009402894,0.0001266193,0.00001117697,0.0000750668,0.00000892456,0.0001299683,0.0001003413,0.00000145691],"category_scores_gemma":[0.00009157965,0.00006599863,0.0001018194,0.0000467469,0.00008150086,0.000003097166,0.00003152597,0.00001954046,6.663055e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00000384936,"about_ca_system_score_gemma":0.00006412621,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002703121,"about_ca_topic_score_gemma":0.00007059149,"domain_scores_codex":[0.9994354,0.00004750126,0.0001594671,0.0001773086,0.00008489162,0.00009543954],"domain_scores_gemma":[0.9995611,0.00001470094,0.0001369815,0.0001570282,0.00009382876,0.00003635232],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006927989,0.00001886029,0.000008625221,0.00001187554,0.00006676149,1.232034e-7,0.00003780323,0.00002709667,0.9912909,0.00264588,0.002640914,0.003181905],"study_design_scores_gemma":[0.0001910863,0.0001434213,0.00005622464,0.000001951695,0.00003877376,0.000002062741,0.00004254512,0.0011575,0.9847006,0.0001905357,0.01339771,0.00007764367],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9532968,0.005343143,0.03937373,0.001266276,0.0001039314,0.000376839,0.0001431692,0.000009134939,0.00008699034],"genre_scores_gemma":[0.9965392,0.0001983405,0.002798381,0.00009343422,0.0001890502,0.00002284497,0.0000769273,0.00001201585,0.00006982212],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0432424,"threshold_uncertainty_score":0.2691346,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03033133839373693,"score_gpt":0.2368353950160991,"score_spread":0.2065040566223622,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}