{"id":"W3082868024","doi":"10.3390/biom10091253","title":"The Morphoregulatory Role of Thidiazuron: Metabolomics-Guided Hypothesis Generation for Mechanisms of Activity","year":2020,"lang":"en","type":"article","venue":"Biomolecules","topic":"Plant tissue culture and regeneration","field":"Biochemistry, Genetics and Molecular Biology","cited_by":58,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Guelph; University of British Columbia, Okanagan Campus; University of British Columbia","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Metabolomics; Metabolism; Thidiazuron; Biochemistry; Phenylpropanoid; Metabolome; Metabolic pathway; Chemistry; Organogenesis; Metabolite; Secondary metabolism; Biology; Tissue culture; Biosynthesis; In vitro; Bioinformatics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006298117,0.0007303419,0.0005809939,0.001043542,0.000258876,0.001257168,0.0006161744,0.0005215697,0.001463992],"category_scores_gemma":[0.0006707992,0.0002584033,0.001073462,0.0005025913,0.0004949933,0.00111144,0.0003826815,0.0004132718,0.0002897746],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006703754,"about_ca_system_score_gemma":0.000746636,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006422997,"about_ca_topic_score_gemma":0.0005984152,"domain_scores_codex":[0.9998858,0.00002252275,0.00000640399,0.00004943796,0.0000194599,0.00001633598],"domain_scores_gemma":[0.9997371,0.0001153271,0.00006825218,0.00001770718,0.00003487976,0.00002660518],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001653967,0.0005436832,0.03499767,0.00350407,0.0006376944,0.002452513,0.00053158,0.06706827,0.7117139,0.02479675,0.001163712,0.1509363],"study_design_scores_gemma":[0.0001523232,0.002249992,0.05399936,0.0003846982,0.0009485277,0.001368354,0.001079419,0.641264,0.2275249,0.05843969,0.0123822,0.0002064336],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.7024677,0.01732668,0.2666603,0.002303363,0.0001033364,0.0005140509,0.002796596,0.001104425,0.006723511],"genre_scores_gemma":[0.9365169,0.0044446,0.05657679,0.0001385843,0.00002838505,0.0001742832,0.001257983,0.00003155565,0.0008309416],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001463992,"threshold_uncertainty_score":0.004897475,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03033133839373693,"score_gpt":0.2368353950160991,"score_spread":0.2065040566223622,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}