{"id":"W3082878036","doi":"10.1371/journal.pone.0237723","title":"Nicotine dependence as a risk factor for upper aerodigestive tract (UADT) cancers: A mediation analysis","year":2020,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Smoking Behavior and Cessation","field":"Medicine","cited_by":11,"is_retracted":false,"has_abstract":true,"ca_institutions":"Public Health Ontario; University Health Network; University of Toronto; Princess Margaret Cancer Centre; Sinai Health System; Lunenfeld-Tanenbaum Research Institute","funders":"Canadian Cancer Society Research Institute; Canada Research Chairs; Princess Margaret Cancer Foundation","keywords":"Medicine; Nicotine; Nicotine dependence; Internal medicine; Lung cancer; Logistic regression; Oncology; Risk factor; Cancer; Mediation; Smoking cessation; Pathology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00472417,0.001406186,0.001091178,0.0008913827,0.0006514327,0.001202029,0.001439241,0.0007802255,0.006048264],"category_scores_gemma":[0.009984909,0.0005035059,0.003784952,0.0006961742,0.0005305305,0.0007972703,0.001782783,0.001374924,0.000295301],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001156731,"about_ca_system_score_gemma":0.003327344,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0328547,"about_ca_topic_score_gemma":0.02485127,"domain_scores_codex":[0.9972801,0.001552689,0.00008307258,0.0004086146,0.000281397,0.000394029],"domain_scores_gemma":[0.995398,0.002718916,0.0005042148,0.000380368,0.0005649615,0.0004335602],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.001347475,0.0004579873,0.9653199,0.000361846,0.005549623,0.0007526013,0.0007185154,0.0006681064,0.0009235259,0.001734201,0.0008501926,0.02131596],"study_design_scores_gemma":[0.0004441034,0.002213094,0.9588139,0.0005188884,0.01452405,0.001232801,0.001687221,0.01049897,0.000961499,0.004556757,0.004486021,0.00006266993],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9704463,0.01263309,0.005408504,0.003030745,0.0002995509,0.0003859725,0.001530387,0.00009559705,0.006169843],"genre_scores_gemma":[0.9958759,0.001450069,0.001043197,0.0001686946,0.00006031283,0.0001195796,0.0002440406,0.000009730618,0.001028488],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0328547,"threshold_uncertainty_score":0.06532693,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08601289019961374,"score_gpt":0.3002830364229912,"score_spread":0.2142701462233775,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}