{"id":"W3082938210","doi":"10.2217/pme-2020-0026","title":"Universal Tumor Screening for Lynch Syndrome: Perspectives of Patients Regarding Willingness and Informed Consent","year":2020,"lang":"en","type":"article","venue":"Personalized Medicine","topic":"Genetic factors in colorectal cancer","field":"Medicine","cited_by":11,"is_retracted":false,"has_abstract":true,"ca_institutions":"St. John’s Health Sciences Centre; Memorial University of Newfoundland","funders":"","keywords":"Lynch syndrome; Informed consent; Medicine; Family medicine; Colorectal cancer screening; Colorectal cancer; Health care; Genetic testing; Oncology; Internal medicine; Alternative medicine; Cancer; Colonoscopy; Pathology; DNA mismatch repair","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.01717795,0.00019362,0.0003766113,0.000533587,0.005123732,0.003523145,0.0005951733,0.002076794,0.004357967],"category_scores_gemma":[0.04937571,0.0001942613,0.0004296813,0.0005113266,0.004687975,0.001711082,0.002428907,0.004403024,0.0003903615],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.005390419,"about_ca_system_score_gemma":0.01443129,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.04956661,"about_ca_topic_score_gemma":0.06467787,"domain_scores_codex":[0.9846863,0.01061899,0.0005631562,0.0003084426,0.001703657,0.002119417],"domain_scores_gemma":[0.9635174,0.01962974,0.004025515,0.0008351204,0.004432803,0.007559406],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"qualitative","study_design_gemma":"observational","study_design_scores_codex":[0.0007121165,0.0004933839,0.3407028,0.0006233223,0.0001608783,0.007025671,0.4537582,0.0005047091,0.003714128,0.01302668,0.05547898,0.1237992],"study_design_scores_gemma":[0.0001902471,0.0009310957,0.1340867,0.002215899,0.0001477875,0.009593601,0.7152866,0.001103378,0.001114298,0.01038359,0.1245983,0.0003484879],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8186902,0.004386134,0.001228384,0.1429962,0.0003741556,0.000221683,0.0001921862,0.00003256866,0.03187844],"genre_scores_gemma":[0.9840544,0.0009465844,0.0005619517,0.0134594,0.00006131952,0.00004251086,0.00003775524,0.000005616109,0.0008304542],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.04956661,"threshold_uncertainty_score":0.09855616,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05041769728069359,"score_gpt":0.3097343313995562,"score_spread":0.2593166341188626,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}