{"id":"W3082953813","doi":"10.1016/j.rmed.2020.106124","title":"Protein succination as a potential surrogate biomarker of airway obstruction. The ilervas project","year":2020,"lang":"en","type":"article","venue":"Respiratory Medicine","topic":"Advanced Glycation End Products research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":false,"ca_institutions":"Queen's University","funders":"Agència de Gestió d'Ajuts Universitaris i de Recerca; European Commission; Federación Española de Enfermedades Raras; Instituto de Salud Carlos III; National Institute for Health and Care Research; Centres de Recerca de Catalunya; Fundación SEEN","keywords":"Medicine; Biomarker; Airway obstruction; Surrogate endpoint; Airway; Intensive care medicine; Internal medicine; Surgery","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004271751,0.0001128586,0.0001358976,0.00005190412,0.00008136551,0.000004807711,0.0002074412,0.00007418794,0.0001172566],"category_scores_gemma":[0.001251434,0.00007517619,0.00004189495,0.0003402006,0.0002408966,0.000007519051,0.00007649913,0.0001177873,0.00001392611],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001260771,"about_ca_system_score_gemma":0.0001911832,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002358439,"about_ca_topic_score_gemma":0.000003309219,"domain_scores_codex":[0.9987189,0.0002006037,0.0002725345,0.0003047945,0.0003432647,0.0001599656],"domain_scores_gemma":[0.9991438,0.00001419398,0.000142925,0.0003286953,0.0002999601,0.0000704449],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003023439,0.00001606035,0.000098444,0.00006555453,0.00003464311,0.00000344575,0.0001281549,0.00004934796,0.9849234,0.0001646077,0.002897644,0.0113164],"study_design_scores_gemma":[0.00120536,0.001055534,0.001876726,0.00003330468,0.00001939836,0.00001088296,0.0003769868,0.0001424627,0.6737397,0.00007662379,0.3213323,0.000130668],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9759956,0.003720042,0.003346734,0.013264,0.0002062211,0.001432611,0.00001617169,0.00003382896,0.001984774],"genre_scores_gemma":[0.9977374,0.00006673532,0.0001673045,0.0007503951,0.0006464657,0.00005296511,0.00004252083,0.00002012835,0.0005160971],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3184347,"threshold_uncertainty_score":0.3065596,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04303664942153591,"score_gpt":0.333399817801219,"score_spread":0.2903631683796831,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}