{"id":"W3083169546","doi":"10.3390/cancers12092542","title":"Neurotrophin Signaling in Medulloblastoma","year":2020,"lang":"en","type":"review","venue":"Cancers","topic":"Nerve injury and regeneration","field":"Neuroscience","cited_by":43,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; SickKids Foundation; Hospital for Sick Children","funders":"Terry Fox Research Institute; Conselho Nacional de Desenvolvimento Científico e Tecnológico; Brain Tumour Foundation of Canada; Coordenação de Aperfeiçoamento de Pessoal de Nível Superior; Genome British Columbia; Canadian Cancer Society Research Institute; National Institutes of Health; Ontario Institute for Cancer Research; Canadian Institutes of Health Research; Pediatric Brain Tumor Foundation; American Brain Tumor Association; Fundação de Amparo à Pesquisa do Estado do Rio Grande do Sul; Genome Canada","keywords":"Trk receptor; Neurotrophin; Tropomyosin receptor kinase A; Tropomyosin receptor kinase B; Tropomyosin receptor kinase C; Low-affinity nerve growth factor receptor; Receptor; Biology; Cancer research; Signal transduction; Neurotrophic factors; Neuroscience; Cell biology; Platelet-derived growth factor receptor; Growth factor; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000215021,0.0006506612,0.0007680404,0.001591571,0.0002087429,0.0005605331,0.0004813956,0.00057543,0.002047765],"category_scores_gemma":[0.0002855495,0.0001543958,0.0003483993,0.001076468,0.0002110925,0.0005544379,0.0004539478,0.0009206113,0.00106359],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006261127,"about_ca_system_score_gemma":0.0008776333,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001788239,"about_ca_topic_score_gemma":0.003498628,"domain_scores_codex":[0.9999256,0.000009409635,0.0000145614,0.00001266582,0.00002926901,0.000008423288],"domain_scores_gemma":[0.9999198,0.0000298049,0.0000176519,0.000002084168,0.00001986139,0.00001080026],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00008460679,0.00004250983,0.000256774,0.01883281,0.0001026774,0.0003849106,0.0000626612,0.0004105425,0.002069951,0.002316373,0.02721857,0.9482176],"study_design_scores_gemma":[0.00002211346,0.0001136517,0.002127671,0.006592372,0.0001951204,0.003769132,0.00005765613,0.0001241037,0.0006446635,0.001957653,0.9843773,0.00001867484],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.000126486,0.9991197,0.00003149531,0.0001010791,0.00008427129,0.000001701913,0.00001168594,0.00000440438,0.0005191619],"genre_scores_gemma":[0.0006776379,0.9987944,0.00004678862,0.00006692356,0.00007457594,0.000002434645,0.00002159484,6.886341e-7,0.0003149274],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002047765,"threshold_uncertainty_score":0.006850481,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08976308727236196,"score_gpt":0.3446071728214403,"score_spread":0.2548440855490783,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}