{"id":"W3083386940","doi":"10.1158/1538-7445.am2020-896","title":"Abstract 896: Enhanced sensitivity detection of replication competent lentivirus by qPCR","year":2020,"lang":"en","type":"article","venue":"Cancer Research","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University College of the North","funders":"","keywords":"Lentivirus; Amplicon; Retrovirus; Vesicular stomatitis virus; Biology; Virology; Genetic enhancement; Plasmid; Chimeric antigen receptor; Virus; Gene; Computational biology; Polymerase chain reaction; Genetics; Cancer; Viral disease","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.005795788,0.001859375,0.001038503,0.001978627,0.0004190333,0.001399069,0.001331314,0.001311335,0.005287249],"category_scores_gemma":[0.004097914,0.0008822334,0.001034842,0.0008493982,0.001198703,0.0008189377,0.0007877906,0.00197651,0.004646301],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001026255,"about_ca_system_score_gemma":0.001336004,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008793548,"about_ca_topic_score_gemma":0.001305426,"domain_scores_codex":[0.9914471,0.002374149,0.0005410084,0.001811629,0.00341065,0.0004155943],"domain_scores_gemma":[0.9969049,0.001187197,0.0004405951,0.0003059525,0.001022944,0.0001384429],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001171292,0.0001351902,0.0008621377,0.0002583893,0.00002368541,0.00003850572,0.00008813979,0.0006353366,0.9858547,0.0005879479,0.0008246012,0.01057415],"study_design_scores_gemma":[0.00001727444,0.0002156189,0.001071413,0.00004511371,0.00002811215,0.0001246031,0.00001840904,0.004473383,0.9879223,0.0001797011,0.005868319,0.00003562599],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"methods","genre_gemma":"empirical","genre_scores_codex":[0.1386844,0.002308378,0.833298,0.0005742346,0.0005594614,0.001994296,0.004542226,0.007446589,0.01059238],"genre_scores_gemma":[0.2408006,0.002535932,0.7114835,0.0007972777,0.0002007385,0.002855948,0.0101955,0.001138321,0.02999217],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.005795788,"threshold_uncertainty_score":0.03065145,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06549577759062106,"score_gpt":0.3892408387869539,"score_spread":0.3237450611963328,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}