{"id":"W3083420153","doi":"10.1158/1538-7445.am2020-5833","title":"Abstract 5833: Senescence is a central response to chemotherapy in ovarian cancer","year":2020,"lang":"en","type":"article","venue":"Cancer Research","topic":"Cancer Research and Treatments","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Espace pour la vie; Université de Montréal","funders":"","keywords":"Senescence; Chemotherapy; Context (archaeology); Cancer research; Medicine; Cancer; DNA damage; Carboplatin; Ovarian cancer; Biology; Oncology; Internal medicine; Cisplatin; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003767011,0.0003132376,0.0004205097,0.0007521072,0.0002789882,0.0005648687,0.0002170186,0.0005507581,0.01070667],"category_scores_gemma":[0.0004370533,0.0001161657,0.0002062259,0.0006852634,0.0002894552,0.0003223526,0.0003775695,0.0005054332,0.002468744],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004720719,"about_ca_system_score_gemma":0.0003720882,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005079596,"about_ca_topic_score_gemma":0.0005837943,"domain_scores_codex":[0.9998401,0.00002905757,0.00002159997,0.00003614755,0.00004429715,0.00002875656],"domain_scores_gemma":[0.9997808,0.0000324733,0.00007473479,0.00001465805,0.00004881123,0.00004847809],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.004213874,0.0003034782,0.06719505,0.003848257,0.0001262692,0.002536522,0.0004855466,0.0003112064,0.5259362,0.002747803,0.05790923,0.3343865],"study_design_scores_gemma":[0.0001584897,0.001940245,0.6940377,0.0005394369,0.0001324587,0.009314964,0.0006018881,0.0005617872,0.1232032,0.001856339,0.1675996,0.00005388895],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8249111,0.1052652,0.004013895,0.01565396,0.003809467,0.0003653519,0.006578354,0.0009355273,0.03846723],"genre_scores_gemma":[0.9144064,0.038639,0.001853238,0.002235357,0.001715141,0.0001872509,0.004565232,0.00009516912,0.03630326],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01070667,"threshold_uncertainty_score":0.03581738,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06116905777116554,"score_gpt":0.4193508444882746,"score_spread":0.358181786717109,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}