{"id":"W3083440507","doi":"10.1158/1538-7445.am2020-1887","title":"Abstract 1887: Tumor-stroma interactions mediated by Semaphorin 6A as a determinant of drug resistance in BRAF-mut melanoma","year":2020,"lang":"en","type":"article","venue":"Cancer Research","topic":"Axon Guidance and Neuronal Signaling","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University Hospital Foundation","funders":"","keywords":"Semaphorin; Melanoma; Cancer research; Stroma; RHOA; Cell culture; Actin cytoskeleton; Biology; Cell; Cell biology; Cytoskeleton; Signal transduction; Immunology; Receptor; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006773104,0.0001312544,0.0001508439,0.0001620463,0.00008716479,0.000149708,0.000074792,0.0001809749,0.001342948],"category_scores_gemma":[0.0000550668,0.00009664176,0.0001514789,0.00008971723,0.00007595016,0.00008074781,0.00009536561,0.0002929212,0.0003666616],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001301841,"about_ca_system_score_gemma":0.00006906583,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004251431,"about_ca_topic_score_gemma":0.0004365982,"domain_scores_codex":[0.9999176,0.00001558034,0.000006977144,0.0000140707,0.0000305471,0.00001522086],"domain_scores_gemma":[0.999954,0.000008737649,0.00001206774,0.000004705828,0.000007608208,0.00001292065],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002510154,0.000008433146,0.0002556514,0.000007880185,0.000001517986,0.00001832822,0.000002544057,0.00001179693,0.9993989,0.000008499053,0.00001081543,0.0002504161],"study_design_scores_gemma":[0.000006625126,0.0002553142,0.02682502,0.000003784998,0.00001272868,0.0004456768,0.00003515662,0.001191927,0.969599,0.00002320103,0.001599371,0.000002334255],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9978404,0.0007231395,0.00056285,0.00004026643,0.00001030148,0.0000118502,0.0002168975,0.0000215166,0.0005727257],"genre_scores_gemma":[0.9967463,0.0003262773,0.000824838,0.00002687274,0.000004492714,0.00001523306,0.0003608426,0.00000710418,0.001687991],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001342948,"threshold_uncertainty_score":0.00449264,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.09261882626044156,"score_gpt":0.3887582903634843,"score_spread":0.2961394641030428,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}